2811-33-8Relevant academic research and scientific papers
Regioselective Synthesis of Δ6-, Δ7-, and Δ8-14α-Cyanosterol Derivatives: Versatile Precursors to 14α-Demethylase Inhibitors
Gallagher, Timothy F.,Adams, Jerry L.
, p. 3347 - 3353 (2007/10/02)
The efficient preparation of 3β-(benzoyloxy)-4,4-dimethyl-5α-cholest-8(14)-en-7-one (4a) and 3β-(benzyloxy)-5α-ergosta-8(14),22-dien-7-one (4b) and their conversion to Δ6-, Δ7- or Δ8-14α-functionalized sterols is reported.
STEROIDAL 14ALPHA-CARBOXY-ALKYL DERIVATIVES AS REGULATORS OF HMG-COA REDUCTASE
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, (2008/06/13)
New 14α-carboxyalkyl sterols are regulators of HMG-CoA reductase and inhibitors of mammalian 14α-methyl demethylase and are useful in lowering serum cholesterol levels and treating fungal infections.
