Journal of the Chemical Society. Chemical communications p. 898 - 900 (1989)
Update date:2022-08-11
Topics:
Cooper, Alan B.
Wright, John J.
Ganguly, Ashit K.
Desai, Jagdish
Loebenberg, David
et al.
Several 14-α-aminomethyl-substituted lanosterol derivatives have been synthesized involving a complete Δ7,8 to Δ8,9 isomerization; these compounds are inhibitors of fungal ergosterol biosynthesis and are active against intact Candida and dermatophyte strains.
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