6384-29-8

Upstream product

• 6384-28-7 4,4-dimethyl-5α-cholest-7-en-3β-ol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 2811-33-8 3β-(Benzoyloxy)-4,4-dimethyl-8α,14α-epoxy-5α-cholestan-7-one 
• 141273-65-6 3β-(Benzoyloxy)-4,4-dimethyl-7α-<(methylsulfonyl)oxy>-5α-cholestane-14α-carbonitrile 
• 141273-69-0 3β-(Benzoyloxy)-8β-hydroperoxy-4,4-dimethyl-7-oxo-5α-cholestane-14α-carbonitrile 
• 141273-70-3 3β-(Benzoyloxy)-8β-hydroxy-4,4-dimethyl-7-oxo-5α-cholestane-14α-carbonitrile 
• 141273-67-8 3β-(Benzoyloxy)-4,4-dimethyl-7-oxo-5α-cholest-8-ene-14α-carbonitrile 
• 141273-64-5 3β-(Benzoyloxy)-4,4-dimethyl-7-oxo-5α-cholestane-14α-carbonitrile 
• 136209-53-5 3β-(Benzoyloxy)-4,4-dimethyl-5α-cholest-7-ene-14α-carbonitrile 
• 136209-54-6 3β-(Benzoyloxy)-4,4-dimethyl-5α-cholest-6-ene-14α-carbonitrile 
• 141318-26-5 3β-(Benzoyloxy)-7α-hydroxy-4,4-dimethyl-5α-cholestane-14α-carbonitrile 
• 14772-54-4 3β-hydroxylanost-7-en-32-al 

Relevant academic research and scientific papers

Regioselective Synthesis of Δ6-, Δ7-, and Δ8-14α-Cyanosterol Derivatives: Versatile Precursors to 14α-Demethylase Inhibitors

The efficient preparation of 3β-(benzoyloxy)-4,4-dimethyl-5α-cholest-8(14)-en-7-one (4a) and 3β-(benzyloxy)-5α-ergosta-8(14),22-dien-7-one (4b) and their conversion to Δ6-, Δ7- or Δ8-14α-functionalized sterols is reported.

STEROIDAL 14ALPHA-CARBOXY-ALKYL DERIVATIVES AS REGULATORS OF HMG-COA REDUCTASE

New 14α-carboxyalkyl sterols are regulators of HMG-CoA reductase and inhibitors of mammalian 14α-methyl demethylase and are useful in lowering serum cholesterol levels and treating fungal infections.