14774-62-0

Upstream product

• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 100-52-7 benzaldehyde 
• 4254-17-5 4-methoxybenzoin 
• 109-77-3 malononitrile 

Downstream Products

• 14774-67-5 5-(4-methoxy-phenyl)-6-phenyl-furo[2,3-d]pyrimidin-4-ylamine 
• 943230-30-6 5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4(3H)-one 
• 1073135-65-5 {[1-({[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}methyl)cyclobutyl]methoxy}-acetic acid 
• 1073135-64-4 {[1-({[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}methyl)cyclobutyl]methoxy}-acetic acid tert-butyl ester 
• 1073134-98-1 (+)-cis-{[(1R,3S)-3-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}cyclopentyl]-oxy}acetic acid tert-butyl ester 
• 943345-29-7 5-(3-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}benzyl)-1,3,4-oxadiazol-2(3H)-one 
• 943345-28-6 4-(2-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid 
• 943345-27-5 4-(2-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid methyl ester 
• 943345-26-4 4-(4-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid 
• 943345-25-3 4-(4-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid methyl ester 
• 943345-24-2 3-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenylacetic acid 
• 943345-23-1 3-(3-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)propanoic acid sodium salt 
• 943345-22-0 3-(3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)propanoic acid 
• 943345-21-9 3-(3-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)propanoic acid methyl ester 

Relevant academic research and scientific papers

An Efficient synthesis of 2-aminofuran-3-carbonitriles via cascade Stetter-γ-ketonitrile cyclization reaction catalyzed by N-heterocyclic carbene

An efficient method for the synthesis of 4,5-disubstituted 2-aminofuran-3-carbonitriles via a cascade Stetter-γ-ketonitrile cyclization reaction of aromatic aldehydes with acylidenemalononitriles, catalyzed by N-heterocyclic carbenes, has been developed.

Novel, Cyclically Substituted Furopyrimidine Derivatives and Use Thereof

The present application relates to novel, cyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.

Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof

The present application relates to novel, acyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.

Ring Transformation and Reactions of 2-Amino-4,5-dihydrofuran-3,4-dicarbonitriles

The 2-amino-4,5-dihydrofuran-3,4-dicarbonitriles (1a-f) were thermally aromatized to the 2-aminofuran-3-carbonitriles (2a-f) which, in turn, underwent photoxidative ring transformation into the 2,5-dihydro-5-hydroxy-2-oxopyrrole-3-carbonitriles (3b-e).Mil