148582-48-3Relevant articles and documents
New practical synthesis of 5-formylindole
Fetter, Jozsef,Bertha, Ferenc,Poszavacz, Laszlo,Simig, Gyula
, p. 137 - 139 (2007/10/03)
5-Formylindole (2) was synthesized in good overall yield starting from 3-methyl-4-nitrobenzaldehyde (4) by utilization of the Batcho-Leimgruber indole synthesis.
Conjugate addition of Grignard reagents to para-substituted nitrobenzenes
Bentley, Stephen J.,Milner, David J.
, p. 1 - 3 (2007/10/02)
Nitrobenzenes bearing masked aldehyde, ketone and ketoester functions at the 4-position undergo conjugate addition with Grignard reagents in THF at -15 deg C.Sequential treatment of the 4-substituted nitrobenzenes with primary or secondary alkyl magnesium