18515-67-8Relevant articles and documents
A mineralogically-inspired silver–bismuth hybrid material: Structure, stability and application for catalytic benzyl alcohol dehydrogenations under continuous flow conditions
?tv?s, Sándor B.,B?sz?rményi, éva,Fül?p, Ferenc,Kónya, Zoltán,Karádi, Krisztina,Kocsis, Marianna,Kukovecz, ákos,Mészáros, Rebeka,Pálinkó, István,Varga, Gábor
, (2020)
In the present contribution, we are reporting our findings on the structure, stability and synthetic applicability of a silver-containing hybrid material, which has recently been introduced by our research groups as a mineralogically-inspired novel heterogeneous catalyst. To determine how silver ions can be fixed into the structure of the catalyst, a set of experiments was designed with modification of the interlayer gallery under hydrothermal conditions. Subsequently, the stability of the material was examined in various solvents under demanding continuous flow conditions with the aim of achieving a clear picture of its applicability in organic syntheses. On the basis of the useful data obtained during the stability tests, a continuous flow methodology was developed for catalytic dehydrogenation of diversely substituted benzylic alcohols. As far as selectivity is concerned the catalyst performed superbly, while the conversions were varied from fair to extremely good.
Selectivity Modulation of the Ley–Griffith TPAP Oxidation with N-Oxide Salts
Moore, Peter W.,Jiao, Yanxiao,Mirzayans, Paul M.,Sheng, Lexter Ng Qi,Hooker, Jordan P.,Williams, Craig M.
, p. 3401 - 3407 (2016/07/26)
A wide variety of novel non-hygroscopic N-oxide tetraphenylborate salts were synthesized and evaluated as co-oxidants in the Ley–Griffith (TPAP) oxidation of benzylic and allylic alcohols under non-anhydrous conditions. The novel DABCOO·TPB (2:1) salt was herein unearthed as a viable competitor to the first-generation NMO·TPB (2:1) salt, but more importantly gave increased performance under oxidative competition. X-ray crystal structure analysis and NMR spectroscopy revealed that depending on the crystallization conditions 1:1, 2:1 or 3:2 N-oxide–tetraphenylborate salts could be formed.
KINASE INHIBITORS
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, (2013/12/03)
The present invention relates to compounds of Formula I or a pharmaceutically acceptable salt thereof, wherein variables R, Ar, X, and Ar1 and n are as defined herein. The compounds are capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.