1488363-22-9

Basic information

• Product Name: (Z)-3-amino-1-(4-bromophenyl)but-2-en-1-one
• Synonyms: (Z)-3-amino-1-(4-bromophenyl)but-2-en-1-one
• CAS NO: 1488363-22-9
• Molecular Weight: 240.099
• Mol File: 1488363-22-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (Z)-3-amino-1-(4-bromophenyl)but-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-amino-1-(4-bromophenyl)but-2-en-1-one(1488363-22-9)
• EPA Substance Registry System: (Z)-3-amino-1-(4-bromophenyl)but-2-en-1-one(1488363-22-9)

Safety Data

• Hazardous Substances Data: 1488363-22-9(Hazardous Substances Data)

Upstream product

• 4023-81-8 1-(p-bromophenyl)-1,3-butanedione 
• 99-90-1 para-bromoacetophenone 
• 178261-64-8 1-(4-bromophenyl)-3-(dimethylamino)but-2-en-1-one 

Downstream Products

• 118097-24-8 4-(4-bromobenzoyl)-5-methyl-1H-imidazol-2(3H)-one 
• 102252-92-6 5-(4-bromobenzoyl)-6-methyl-2(1H)-pyridinone 

Relevant articles and documents

Reactions of methyl ketones and (hetero)arylcarboxamides with N,N-dimethylacetamide dimethyl acetal. A simple metal-free synthesis of 2,4,6-trisubstituted pyridines

Two metal-free syntheses of 2,4,6-trisubstituted pyridines 10a-m and 16a-j are described. N,N,6-Trimethyl-4-(substituted)pyridin-2-amines 10 were prepared from aryl or heteroaryl methyl ketones which were transformed with N,N-dimethylacetamide dimethyl ac

Formation of functionalized 2H-azirines through phio-mediated trifluoroethoxylation and azirination of enamines

A variety of enaminones and enamine carboxylic esters were converted to trifluoroethoxylated 2H-azirines through reactions with PhIO in trifluoroethanol (TFE). The cascade reaction is postulated to proceed via a PhIO-mediated oxidative trifluoroethoxylation and a subsequent azirination of the α-trifluoroethoxylated enamine intermediates.