178261-64-8Relevant academic research and scientific papers
A simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl]fumarates: Potential intermediates in the synthesis of polysubstituted five- and six-membered heterocycles
?inkovec, Rok,Gro?elj, Uro?,Prek, Benjamin,Po?kaj, Marta,Ri?ko, Sebastijan,Svete, Jurij,Stanovnik, Branko
, p. 677 - 682 (2016/07/06)
In this communication, a simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl] fumarates is described. Methyl ketones were transformed by treatment with N,N-dimethylacetamide dimethyl acetal (DMADMA) into 3-dimethylamino-1-(subst
Reactions of methyl ketones and (hetero)arylcarboxamides with N,N-dimethylacetamide dimethyl acetal. A simple metal-free synthesis of 2,4,6-trisubstituted pyridines
Prek, Benjamin,Groelj, Uro,Kasuni, Marta,Zupani, Silvo,Svete, Jurij,Stanovnik, Branko
, p. 184 - 195 (2015/02/19)
Two metal-free syntheses of 2,4,6-trisubstituted pyridines 10a-m and 16a-j are described. N,N,6-Trimethyl-4-(substituted)pyridin-2-amines 10 were prepared from aryl or heteroaryl methyl ketones which were transformed with N,N-dimethylacetamide dimethyl ac
Clean and efficient synthesis of isoxazole derivatives in aqueous media
Dou, Guolan,Xu, Pan,Li, Qiang,Xi, Yukun,Huang, Zhibin,Shi, Daqing
, p. 13645 - 13653 (2014/01/06)
A series of 5-arylisoxazole derivatives were synthesized via the reaction of 3-(dimethyl-amino)-1-arylprop-2-en-1-ones with hydroxylamine hydrochloride in aqueous media without using any catalyst. This method has the advantages of easier work-up, mild rea
NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
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Page/Page column 32; 33, (2010/04/23)
The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.
