348-59-4

Basic information

• Product Name: 2,5-DICHLOROFLUOROBENZENE
• Synonyms: 2,5-DICHLOROFLUOROBENZENE;1,4-DICHLORO-2-FLUOROBENZENE;Benzene,1,4-dichloro-2-fluoro-;1,4-Dichloro-2-fluorobenzene, 99+%;2,5-dichloro-1-fluorobenzene;2,5-Dichlorofluorobenzene 98%;2,5-Dichlorofluorobenzene98%;1,4-Dichloro-2-fluorobenzene, 99+% 5GR
• CAS NO: 348-59-4
• Molecular Formula: C₆H₃Cl₂F
• Molecular Weight: 164.99
• Product Categories: Other fluorin-contained compounds;Chlorine Compounds;Fluorine Compounds;Fluorine series
• Mol File: 348-59-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 4 °C
• Boiling Point: 168 °C
• Flash Point: 65 °C
• Appearance: clear colorless liquid
• Density: 1.383
• Refractive Index: 1.5235-1.5255
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Difficult to mix.
• BRN: 2355590
• CAS DataBase Reference: 2,5-DICHLOROFLUOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROFLUOROBENZENE(348-59-4)
• EPA Substance Registry System: 2,5-DICHLOROFLUOROBENZENE(348-59-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• RIDADR: 1992
• PackingGroup: III
• Hazardous Substances Data: 348-59-4(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLORLESS LIQUID

Uses

1,4-Dichloro-2-fluorobenzene is used as organic synthesis intermediates

InChI:InChI=1S/C6H3Cl2F/c7-4-1-2-5(8)6(9)3-4/h1-3H

Upstream product

• 351-31-5 N-(4-chloro-3-fluorophenyl)acetamide 
• 351-28-0 N-(3-fluorophenyl)acetamide 
• 13656-50-3 2,5-dichloro-4-fluorobenzenesulfonyl chloride 
• 36556-50-0 2,3-dichlorofluorobenzene 
• 106-46-7 para-dichlorobenzene 
• 367-22-6 4-chloro-3-fluoroaniline 

Downstream Products

• 1056987-14-4 C₁₈H₁₈Cl₂O₃ 
• 1894-96-8 1-(2,5-dichloro-4-fluoro-phenyl)ethanone 
• 1612259-17-2 1-[2,5-dichloro-4-(4-chlorophenoxy)phenyl]ethanone 
• 1612259-11-6 1-[2-[2,5-dichloro-4-(4-chlorophenoxy)phenyl]-2-methoxy-propyl]-1,2,4-triazole 
• 1612259-10-5 2-[2,5-dichloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol 
• 1612259-18-3 2-[2,5-dichloro-4-(4-chlorophenoxy)phenyl]-2-methyl-oxirane 
• 1638159-46-2 5-(3,6-dichloro-2-fluorophenyl)pyrimidine 
• 1638159-37-1 (3’,6’-dichloro-2’-fluorobiphenyl-4-yl)phenylmethanone 
• 1638159-44-0 4-(3,6-dichloro-2-fluorophenyl)pyridine 
• 1638159-43-9 3-(3,6-dichloro-2-fluorophenyl)pyridine 
• 1638159-45-1 3-(3,6-dichloro-2-fluorophenyl)quinoline 
• 1638159-36-0 3’,6’-dichloro-2’-fluorobiphenyl-4-carbaldehyde 
• 5292-47-7 1,4-dimethyl 2-fluorobenzene-1,4-dicarboxylate 
• 148893-72-5 4-chloro-2-fluorobenzoic acid methyl ester 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ORGANIC HALIDES

The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.

Photo-Rearrangement of Polychlorobenzenes meta-Migration of Chlorine Atom

Several polychlorobenzenes were irradiated by ultraviolet light (254 nm) in acetonitrile and the products were determined by gas chromatography.In addition to the abstraction of hydrogen atom from the solvent, photo-isomerization was shown to proceed giving isomeric polychlorobenzenes one of which chlorine atoms migrated to meta to the original position.The meta-rearrangement was rationalized by an MNDO calculation on o-chlorophenyl free radical.