1490-44-4

Basic information

• Product Name: 3-CHLORO-6-PHENOXYPYRIDAZINE
• Synonyms: 3-CHLORO-6-PHENOXYPYRIDAZINE
• CAS NO: 1490-44-4
• Molecular Formula: C₁₀H₇ClN₂O
• Molecular Weight: 206.63
• Mol File: 1490-44-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 363.2°C at 760 mmHg
• Flash Point: 173.4°C
• Appearance: /
• Density: 1.304g/cm³
• Vapor Pressure: 3.84E-05mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 3-CHLORO-6-PHENOXYPYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-6-PHENOXYPYRIDAZINE(1490-44-4)
• EPA Substance Registry System: 3-CHLORO-6-PHENOXYPYRIDAZINE(1490-44-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1490-44-4(Hazardous Substances Data)

Usage

General Description

3-Chloro-6-phenoxypyridazine is a chemical compound with the molecular formula C11H7ClN2O. It is a chlorinated pyridazine derivative, and is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its chemical structure consists of a pyridazine ring with a chlorine atom at position 3 and a phenoxyl group at position 6. 3-CHLORO-6-PHENOXYPYRIDAZINE has the potential to be used as a building block in the development of new drugs and pesticides, and its properties make it suitable for a range of applications in the chemical industry.

InChI:InChI=1/C10H7ClN2O/c11-9-6-7-10(13-12-9)14-8-4-2-1-3-5-8/h1-7H

Upstream product

• 1677-80-1 3,4-dicholoropyridazine 
• 108-95-2 phenol 
• 141-30-0 3,6-dichlorpyridazine 

Downstream Products

• 1231995-31-5 C₂₂H₁₆N₆O₂ 
• 1231995-30-4 C₂₈H₂₇BN₆O₃ 
• 1234349-65-5 2-[3-(5-methyl-1,2,4-oxadiazol-3-yl)benzyl]-6-phenoxy-2H-pyridazin-3-one 
• 1231995-17-7 C₁₈H₁₃BrN₄O 
• 1231995-18-8 C₂₄H₂₅BN₄O₃ 
• 1231995-05-3 3-{3-[5-(2-morpholin-4-ylethoxy)pyrimidin-2-yl]-benzyl}-6-phenoxy-1,2,4-triazolo[4,3-b]pyridazine 
• 1231994-95-8 6-phenoxy-3-(3-{5-[1-(2-pyrrolidin-1-ylethyl)-1H-pyrazol-4-yl]pyrimidin-2-yl}benzyl)-1,2,4-triazolo[4,3-b]pyridazine 
• 1231994-80-1 3-[3-(5-bromopyrimidin-2-yl)benzyl]-6-phenoxy-1,2,4-triazolo[4,3-b]pyridazine 
• 10340-55-3 3,6-diphenoxypyridazine 
• 1788-55-2 6-phenoxypyridazin-3(2H)-one 
• 5639-03-2 3-Phenoxy-pyridazin 

Relevant articles and documents

Histone deacetylase inhibitor taking pyridazinone as mother nucleus structure, and preparation method and applications thereof

The invention discloses a histone deacetylase inhibitor taking pyridazinone as a mother nucleus structure, and a preparation method and applications thereof. The structure of the inhibitor is shown asa formula I; and the compound shown as the formula I has good histone deacetylase inhibitory activity and anti-tumor cell proliferation effects, and can be used for treating cancers. The structure ofthe inhibitor is shown as the formula I.

3-Quinuclidinyl heteroatom bridged biaryl derivatives

Compounds of formula: or pharmaceutically acceptable salts, esters, amides, or prodrugs thereof, wherein: A and G are each independently N or N+—O?; m and n are each independently 0, 1, or 2; X1 and X3 are each independently O, S, and —N(R1)—; X2 is O, S, —N(R1)—, —N(Ar2)—, and —N(R2)C(O)—; Ar1 is a six-membered aromatic ring; Ar2 is cyclohexyl or a mono- or bicyclic aromatic ring, and R13 is hydrogen, alkyl, or halogen, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formulas (I) and (II) and methods for using such compounds and compositions.