1677-80-1

Basic information

• Product Name: 3,4-dichloropyridazine
• Synonyms: 3,4-dichloropyridazine
• CAS NO: 1677-80-1
• Molecular Formula: C₄H₂Cl₂N₂
• Molecular Weight: 148.97808
• EINECS: -0
• Mol File: 1677-80-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 284.8°Cat760mmHg
• Flash Point: 153.2°C
• Appearance: /
• Density: 1.493g/cm³
• Vapor Pressure: 0.00501mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.89±0.10(Predicted)
• CAS DataBase Reference: 3,4-dichloropyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dichloropyridazine(1677-80-1)
• EPA Substance Registry System: 3,4-dichloropyridazine(1677-80-1)

Safety Data

• Hazardous Substances Data: 1677-80-1(Hazardous Substances Data)

Usage

General Description

3,4-dichloropyridazine is a chemical compound with the molecular formula C4H2Cl2N2. It is a member of the pyridazine family, which is a six-membered heterocyclic compound containing two nitrogen atoms and four carbon atoms in the ring. 3,4-dichloropyridazine is a white to light yellow crystalline solid, and it is insoluble in water but soluble in organic solvents such as ethanol and acetone. It is primarily used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds. Additionally, it has been found to have applications in the field of materials science and organic synthesis due to its reactivity and versatile chemical properties. However, it is important to handle 3,4-dichloropyridazine with care, as it may pose health and environmental risks if not properly managed.

InChI:InChI=1/C4H2Cl2N2/c5-3-1-2-7-8-4(3)6/h1-2H

Upstream product

• 1677-79-8 4-chloropyridazin-3-ol 
• 504-30-3 3-hydroxypyridazine 

Downstream Products

• 1490-44-4 3-chloro-6-phenoxy-pyridazine 
• 1415050-22-4 C₁₀H₈ClN₃O 

Relevant articles and documents

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A 3,4- [...] method for the synthesis of

The invention discloses a novel synthesis method of 3,4-dichloropyridazine. The 3,4-dichloropyridazine 4 is prepared through reaction between a compound 3 and POCl3 in an isopropanol solvent, the compound 3 is prepared through reaction between a compound 2 and MnO2 in a tetrahydrofuran solvent, and the compound 2 is prepared through reaction between a compound 1 and hydrazine hydrate in an acetonitrile solvent, wherein preferred conditions are as follows: a mol ratio of the hydrazine hydrate to the compound 1 is 1.1 to 1, the reaction temperature is 25-30 DEG C, the time is 6h; a mol ratio of MnO2 to the compound 2 is 4 to 1, the reaction temperature is 25 DEG C, the time is 8h; a mol ratio of the POCl3 to the compound 2 is 2.5 to 1, the reflowing reaction temperature is 80 DEG C, and the time is 3h. The synthesis method has the advantages that the raw materials are easily available, reaction conditions are mild, operability in post-treatment is good, the yield is relatively high, the production is easily enlarged, and thus the novel synthesis method is especially suitable for industrial large-scale production.