149105-10-2

Basic information

• Product Name: 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE
• Synonyms: 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE;4-METHOXY-3-(TRIFLUOROMETHYL)ACETOPHENONE;1-(3-(TRIFLUOROMETHYL)-4-METHOXYPHENYL)ETHANONE;1-[4-Methoxy-3-(trifluoromethyl)phenyl]ethan-1-one;1-[4-Methoxy-3-(trifluoromethyl)phenyl]ethan-1-one, 5-Acetyl-2-methoxybenzotrifluoride, 4-Acetyl-2-(trifluoromethyl)anisole;1-(4-Methoxy-3-(trifluoroMethyl)phenyl)ethanone;4'-Methoxy-3'-(trifluoromethyl)acetophenone 98+%
• CAS NO: 149105-10-2
• Molecular Formula: C₁₀H₉F₃O₂
• Molecular Weight: 218.17
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 149105-10-2.mol

Chemical Properties

• Boiling Point: 259.2±40.0℃ (760 Torr)
• Flash Point: 107.3±22.2℃
• Appearance: /
• Density: 1.222±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE(149105-10-2)
• EPA Substance Registry System: 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE(149105-10-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 149105-10-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE is used as a synthetic reagent for the production of triazoles, which are known for their anti-hepatoma (liver cancer) activity. The compound plays a crucial role in the development of new drugs targeting liver cancer, contributing to the advancement of cancer treatment options.
In the synthesis process, 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE serves as a key intermediate, enabling the creation of triazoles with potential anti-cancer properties. These triazoles can modulate various oncological signaling pathways, exerting inhibitory effects on tumor growth and progression. The use of 4'-METHOXY-3'-(TRIFLUOROMETHYL)ACETOPHENONE in pharmaceutical research and development highlights its importance in the fight against cancer, particularly liver cancer.

Upstream product

• 149105-11-3 1-[4-hydroxy-3-(trifluoromethyl)phenyl]ethan-1-one 
• 74-88-4 methyl iodide 
• 851262-98-1 1-[4-methyl-3-(trifluoromethyl)phenyl]ethanone 
• 124-41-4 sodium methylate 
• 208173-24-4 1-(4-fluoro-3-(trifluoromethyl)phenyl)ethanone 
• 261951-87-5 4-methoxy-3-(trifluoromethyl)benzonitrile 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 541550-00-9 2-bromo-1-(4-methoxy-3-(trifluoromethyl)phenyl)ethanone 

Relevant articles and documents

HETEROCYCLIC COMPOUND, PREPARATION METHOD AND USE THEREOF IN MEDICINE

Provided are a heterocyclic compound, a preparation method and the use thereof in medicine, and particularly involved are a heterocyclic compound for preventing and/or treating hypemricemia and gout, a preparation method and the use thereof in medicine. I

COMPOUND FOR TREATING OR PREVENTING HYPERURICEMIA OR GOUT

Provided are a compound as represented in formula (I), a pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and uses thereof. The compound as represented in formula (I) and the pharmaceutically acceptable salts thereof are used in the preparation of medicines for the treatment or prevention of hyperuricemia or gout by means of uric acid excretion.

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is a novel amine compound represented by the following formula (I) having a superior peripheral blood lymphocyte decreasing action and superior in the immunosuppressive action, rejection suppressive action and the like, which shows decreased side effects of, for example, bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof. wherein each symbol is as defined in the specification.

AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES

A novel amine compound represented by the following formula (I), which is superior in immunosuppressive action, rejection suppressive action and the like, and shows reduced side effects such as bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or hydrates thereof, or solvate, as well as a pharmaceutical composition containing this compound and a pharmaceutically acceptable carrier. wherein R is a hydrogen atom or P(=O)(OH)2, X is an oxygen atom or a sulfur atom, Y is CH2CH2 or CH=CH, R1 is cyano or alkyl having a carbon number of 1 to 4 and substituted by a halogen atom(s), R2 is alkyl having a carbon number of 1 to 4 and optionally substituted by a hydroxyl group(s) or a halogen atom(s), R3 and R4 may be the same or different and each is a hydrogen atom or alkyl having a carbon number of 1 to 4, and n is 5 - 8.

1,3-Diphenylprop-2-En-1-One Derivative Compounds, Preparation Method Thereof and Uses of Same

The invention relates to substituted 1,3-diphenylprop-2-en-1-one derivative compounds, pharmaceutical and/or cosmetic compositions containing same, and the applications thereof in therapeutics and cosmetics. The invention also relates to a method for prep