149228-51-3Relevant academic research and scientific papers
A concise and enantioselective synthesis of novel HIV-1 protease transition state mimics
Dorsey,Plzak,Ball
, p. 1851 - 1854 (1993)
Novel HIV-1 protease inhibitors have been prepared in an enantioselective manner via an Evans asymmetric aldol, Claisen rearrangement and iodolactonization. X-ray crystallographic analysis was used to confirm the absolute configuration of the newly created stereogenic centers.
