149253-60-1

Basic information

• Product Name: ethyl (1'S,2R,5R)-1-benzyloxycarbonyl-3-(1'-phenyl-1'-ethyl)-5-(3-ethoxycarbonylpropyl)imidazolidin-4-one-2-carboxylate
• Synonyms: ethyl (1'S,2R,5R)-1-benzyloxycarbonyl-3-(1'-phenyl-1'-ethyl)-5-(3-ethoxycarbonylpropyl)imidazolidin-4-one-2-carboxylate
• CAS NO: 149253-60-1
• Molecular Weight: 510.587
• Mol File: 149253-60-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (1'S,2R,5R)-1-benzyloxycarbonyl-3-(1'-phenyl-1'-ethyl)-5-(3-ethoxycarbonylpropyl)imidazolidin-4-one-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (1'S,2R,5R)-1-benzyloxycarbonyl-3-(1'-phenyl-1'-ethyl)-5-(3-ethoxycarbonylpropyl)imidazolidin-4-one-2-carboxylate(149253-60-1)
• EPA Substance Registry System: ethyl (1'S,2R,5R)-1-benzyloxycarbonyl-3-(1'-phenyl-1'-ethyl)-5-(3-ethoxycarbonylpropyl)imidazolidin-4-one-2-carboxylate(149253-60-1)

Safety Data

• Hazardous Substances Data: 149253-60-1(Hazardous Substances Data)

Upstream product

• 134746-24-0 ethyl (S,R)-N-benzyloxycarbonyl-N'-(β-phenethyl)-α,α-diaminoacetate 
• 134746-23-9 ethyl 2-(((benzyloxy)carbonyl)amino)-2-chloroacetate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 134746-26-2 ethyl (S,R)-N-benzyloxycarbonyl-N'-acryloyl-N'-(β-phenethyl)-α,α-diaminoacetate 
• 140-88-5 ethyl acrylate 

Downstream Products

• 7620-28-2 D-2-aminoadipic acid 

Relevant articles and documents

TOTAL SYNTHESIS OF ENANTIOMERICALLY PURE D-α-AMINOADIPIC ACID

The diastereoselective cyclization of amidal (S,R)-2a, promoted by Hg(OTFA)2, afforded the imidazolidin-4-one (1'S,2R,5R)-3a as a single diastereoisomer. The subsequent transformation of the carbon-mercury bond and the acid hydrolysis of the heterocycle gave enantiomerically pure D-α-aminoadipic acid.