149310-61-2Relevant articles and documents
Further enolate alkylation studies of 2,5-dimethyl-3(2H)-furanone
Caine, Drury S.,Arant, Mark E.
, p. 2081 - 2086 (2007/10/03)
Heterocyclic ketones, such as 2,5-dimethyl-3(2H)-furanone, provide multifunctional intermediates to various compounds. One property of these that has proven useful is the ability to alkylate the γ′-position of the dienolate. This report demonstrates the versatility of γ′-dienolate substitutions as employed toward syntheses of certain natural products and highly reactive electrophiles provide the best substrates for efficient substitution.
New Syntheses of Geiparvarin and 2,5-Dimethyl-3(2H)-furanone via CO2 Mediated Bond Reorganization
Inoue, Y.,Ohuchi, K.,Imaizumi, S.,Hagiwara, H.,Uda, H.
, p. 3063 - 3068 (2007/10/02)
A new synthesis of 3(2H)-furanones from 4-hydroxy-2-alkyn-1-one derivatives via CO2 mediated bond reorganization has been developed to the preparation of an antitumor agent, geiparvarin and a constituent of flavors, 2,5-dimethyl-3(2H)-furanone.
An Unusual Substitution Reaction in a Benzotetrazine Derivative
Almerico, A. M.,Boulton, A. J.
, p. 204 - 205 (2007/10/02)
1-Methyl-3H-pyrazolobenzotetrazin-3-one decomposes in alcohols, with loss of nitrogen and intramolecular hydrogen transfer, to form 5-alkoxymethyl-1,2-dihydro-1-phenyl-3H-pyrazol-3-ones.
