1494-29-7

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 459-56-3 4-fluorobenzylic alcohol 
• 31913-41-4 6-methyl-4-tosyloxy-2(2H)-pyranone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 200055-89-6 4-(4-toluenesulfonyloxy)coumarin 
• 210422-66-5 4-fluorobenzaldehyde p-toluenesulfonylhydrazone 
• 459-57-4 4-fluorobenzaldehyde 
• 10486-08-5 sodium p-thiocresolate 
• 1426-53-5 1-fluoro-4-((p-tolylsulfinyl)methyl)benzene 
• 1494-33-3 4-fluorobenzyl(4-methylphenyl)sulfane 

Downstream Products

• 1136166-70-5 p-fluorophenyl(phenyl)methyl p-tolyl sulfone 
• 1563173-91-0 C₂₁H₁₆F₂O₂S 

Relevant academic research and scientific papers

Kinetic resolution in vanadium-catalyzed sulfur oxidation as an efficient route to enantiopure aryl benzyl sulfoxides

Enantiopure aryl benzyl sulfoxides can be prepared using vanadium-Schiff base catalyzed sulfide oxidation and kinetic resolution of the resulting sulfoxide. The kinetic resolution can be effected in combination with asymmetric sulfide oxidation or instead starting from the racemic sulfoxide. Georg Thieme Verlag Stuttgart.

Synthesis of sulfone derivatives via palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides

A palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides for the synthesis of various benzyl sulfones is reported. This novel protocol shows widespread functional group tolerance, leading to the desired sulfones in moderate to excellent yields.

Visible-Light-Catalyzed in Situ Denitrogenative Sulfonylation of Sulfonylhydrazones

A photocatalyzed in situ denitrogenative sulfonylation of N-arylsulfonyl hydrazones has been developed. This transformation provides a low-carbon strategy to assemble arylalkyl sulfones in a stepwise denitrogenation/sulfonylation manner.

Iron(III) phthalocyanine-chloride-catalyzed synthesis of sulfones from sulfonylhydrazones

In this study, sulfones are synthesized from sulfonylhydrazones catalyzed by iron(III) phthalocyanine chloride. This reaction offers broad substrate scope, occurs under mild conditions, utilized readily available reactants, and forms products in good-to-h

Application of the polyacrylonitrile fiber as a support for the green heterogeneous base catalyst and supported phase-transfer catalyst

A facile synthesized polyethylene polyamine functionalized polyacrylonitrile fiber (PANF-PA), capable of acting as the heterogeneous base catalyst and supported phase-transfer catalyst (SPTC), was presented in Knoevenagel condensation-cyclization and nucleophilic substitution for the synthesis of a number of substituted iminocoumarins and sulfones in aqueous systems, respectively. Excellent results are shown in terms of simple procedures, high chemical yields (up to 96%), extensive applicability and superior catalytic recyclability even for 10 cycles. The deeper active principle of the PANF-PA as SPTC was explained through detailed characterization by means of elemental analysis, FTIR spectroscopy and SEM. Moreover, the procedures can be effectively scaled up, and the solvent can be easily recovered. As well as, the prominent features (high strength, good flexibility etc.) of the polyacrylonitrile fiber are very attractive for fixed-bed reactors in the chemical industry. This journal is

Iron (III) chloride-catalyzed direct sulfonylation of alcohols with sodium arenesulfinates

A new protocol for the direct sulfonylation of benzylic, allylic and homoallylic alcohols with sodium arenesulfinates is described by using iron (III) chloride as a catalyst and chlorotrimethylsilane as an additive. This method requires no preactivation o

Palladium-catalyzed benzylic direct arylation of benzyl sulfones with aryl halides

An effective palladium catalyst system for the direct arylation of benzyl sulfones with aryl halides has been developed. The catalytic reaction provides a facile route to diarylmethyl sulfones. The products can be transformed further via desulfonylative functionalization mediated by aluminum compounds.

Asymmetric synthesis of aryl benzyl sulfoxides by vanadium-catalysed oxidation: A combination of enantioselective sulfide oxidation and kinetic resolution in sulfoxide oxidation

Enantioselective vanadium-catalysed oxidation of aryl benzyl sulfides using Bolm's procedure is accompanied by kinetic resolution in the oxidation of the resulting sulfoxides which enhances the enantiopurities of the sulfoxides recovered (typically >90% ee), albeit with an associated reduction in yield. The effects of ligand, solvent and reaction conditions are discussed in detail. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.