14960-82-8

Upstream product

• 622-97-9 1-ethenyl-4-methylbenzene 
• 105-74-8 dilauryl peroxide 
• 766-97-2 4-n-methylphenylacetylene 
• 537653-09-1 1-methoxytridec-1-ene 
• 380481-66-3 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane 
• 92-54-6 4-phenyl-1-piperazine 
• 32316-92-0 naphthalene-2-boronic acid 
• 7657-86-5 tri(naphthalen-2-yl) phosphate 
• 93-04-9 2-Methoxynaphthalene 
• 580-13-2 2-bromonaphthalene 
• 494-03-1 N,N-bis(2-chloroethyl)-2-naphthylamine 
• 62-53-3 aniline 

Relevant academic research and scientific papers

Iron-Catalyzed Vinylic C?H Alkylation with Alkyl Peroxides

A variety of alkyl peresters and alkyl diacyl peroxides, which are readily accessible from carboxylic acids, are utilized as general primary, secondary, and tertiary alkylating reagents for iron-catalyzed vinylic C?H alkylation of vinyl arenes, dienes, and 1,3-enynes. This transformation affords olefinic products in up to 98 % yield with high E/Z values. A broad range of functionalities, including carboxyl, boronic acid, methoxy, ester, amino, and halides, are tolerated. This protocol provides a facile approach to some olefins that are difficult to access, and hence, offers an alternative to existing systems. The synthetic utility of this method is demonstrated by late-stage functionalization of selected natural-product derivatives.

Hydroalkylation of terminal aryl alkynes with alkyl diacyl peroxides

A photo and nickel co-catalyzed hydroalkylation of terminal aryl alkynes enabled Z-preferred olefin synthesis has been developed under mild conditions. Alkyl diacyl peroxides were utilized as a new type of alkylation reagents and afforded Z-olefins as the major products in moderate to good yields.

N-(Pyridin-2-yl)benzamide: Efficient ligand for the nickel catalyzed Chan-Lam cross-coupling reaction

An efficient protocol for the Chan-Lam cross-coupling reactions of arylboronic acids with aryl or alkyl amines has been developed by employing simple N-(pyridin-2-yl)benzamide ligand with Ni(OAc)2·4H2O in the presence of TMG base. The reaction proceeded well with high yields by employing various N-nucleophiles at low catalytic loadings.

Nickel-catalyzed amination of aryl phosphates through cleaving aryl C-O bonds

The amination of triaryl phosphates was achieved using a Ni(II)-(σ-Aryl) complex/NHC catalyst system in dioxane at 110 °C in the presence of NaH as base. Electron-neutral, -rich, and -deficient triaryl phosphates were coupled with a wider range of amine partners including cyclic and acyclic secondary amines, aliphatic primary amines, and anilines in good to excellent yields.

Ni0-catalyzed direct animation of anisoles involving the cleavage of carbon-oxygen bonds

Ni0-catalyzed cross-coupling of aryl methyl ethers with amines is described. The use of an N-heterocyclic carbene as a ligand and NaOt-Bu as a base promotes the amination of anisole derivatives via the cleavage of normally unreactive aryl carbo

Nickel-catalyzed cross-coupling reaction of alkenyl methyl ethers with aryl boronic esters

The Ni(0)-catalyzed cross-coupling of alkenyl methyl ethers with boronic esters is described. Several types of alkenyl methyl ethers can be coupled with a wide range of boronic esters to give the stilbene derivatives.

Microwave-assisted synthesis of substituted phenanthrenes, anthracenes, acenaphthenes, and fluorenes

Rapid coupling reactions of polycyclic aromatic halides with various N-, S-, and Se-nucleophiles under focused microwave irradiation are described. Using this method, the desired products are obtained with good to excellent yields in a short reaction time. Crown Copyright