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Usage

Uses

Used in Pharmaceutical Industry:
Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)is used as a key intermediate in the synthesis of various pharmaceutical drugs due to its complex structure and functional groups. The presence of hydroxyl and methoxy groups can facilitate the creation of new bioactive molecules with potential therapeutic effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)serves as a versatile building block for the development of novel compounds with specific properties. Its structural components can be manipulated to create a variety of chemical entities for different applications.
Used in Antioxidant Applications:
Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)is used as an antioxidant in various industries, including food and cosmetics, to prevent oxidation and extend the shelf life of products. The hydroxy and methoxy groups on the phenyl ring may contribute to its antioxidant capacity.
Used in Antimicrobial Applications:
Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)is utilized as an antimicrobial agent in applications where control of microbial growth is necessary, such as in medical settings or in the preservation of perishable goods. The presence of functional groups may interact with microbial cell structures, inhibiting their growth and activity.
Used in Anti-inflammatory Applications:
Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)may be used in anti-inflammatory formulations to reduce inflammation and associated symptoms. Ethanone,1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)-'s structure suggests it could modulate inflammatory responses, although further research is required to explore this application fully.

Upstream product

• 855155-95-2 4-acetoxy-2,6-dimethoxy-toluene 
• 52200-61-0 2,4-dihydroxy-6-methoxy-5-methyl-acetophenone 
• 74-88-4 methyl iodide 
• 22080-97-3 3,5-dimethoxy-4-methylphenol 
• 75-36-5 acetyl chloride 
• 2657-28-5 2,4,6-trihydroxy-3-methyl-acetophenon 
• 77-78-1 dimethyl sulfate 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 487-70-7 2,4,6-trihydroxybenzaldehyde 
• 88-03-9 2,4,6-trihydroxytoluene 
• 98-88-4 benzoyl chloride 
• 102749-22-4 1-(4,6-bis-benzyloxy-2-methoxy-3-methyl-phenyl)-ethanone 
• 22080-96-2 syringaldehyde 
• 500-99-2 3,5-dimethoxyphenol 

Downstream Products

• 21568-25-2 6'-hydroxy-4,2',4'-trimethoxy-3'-methyl-trans-chalcone 
• 100211-00-5 5,7-dimethoxy-3-(2-methoxyphenyl)-6-methyl-4H-chromen-4-one 
• 78278-21-4 2-acetyl-4-methyl-3,5-dimethoxyphenyl 3-iodo-p-anisate 
• 61110-43-8 6-C-methylhexa-O-methylamentoflavone 
• 78278-23-6 6-C-methyl-3'-iodo-4',5,7-trimethoxyflavone 

Relevant academic research and scientific papers

Concise synthesis and cellular evaluation of 3′-formyl-4′,6′-dihydroxy-2′-methoxy-5′-methylchalcone (FMC) and its analogues

3′-Formyl-4′,6′-dihydroxy-2′-methoxy-5′-methylchalcone (FMC) was a natural product isolated from Cleistocalyx operculatus. A four-step synthetic strategy toward FMC and its four analogues (1b-1e) was first developed. All compounds were synthesized from commercially available 2,4,6-trihydroxyacetophenone; formylation at 3′ position under Vilsmeier-Haack conditions was followed by the introduction of a methyl group at 5′ position. The key step of selective methylation at 2′ position was achieved by trimethylsilyldiazomethane (TMSCHN2). Then substituted aromatic aldehydes were condensed through Claisen-Schmidt reaction in the presence of potassium hydroxide. All structures were confirmed by 1H NMR, 13C NMR, and high-resolution mass spectra. FMC and analogues were screened for their antiproliferative activity.

Isolation, Synthesis, and Antisepsis Effects of a C-Methylcoumarinochromone Isolated from Abronia nana Cell Culture

Only a few isoflavones have been isolated from plants of the genus Abronia. The biological properties of compounds isolated from Abronia species have not been well established, and their antisepsis effects have not been reported yet. In the present study, a new C-methylcoumarinochromone, was isolated from Abronia nana suspension cultures. Its structure was deduced as 9,11-dihydroxy-10-methylcoumarinochromone (boeravinone Y, 1) by spectroscopic data analysis and verified by chemical synthesis. The potential inhibitory effects of 1 against high mobility group box 1 (HMGB1)-mediated septic responses were investigated. Results showed that 1 effectively inhibited lipopolysaccharide-induced release of HMGB1 and suppressed HMGB1-mediated septic responses, in terms of reduction of hyperpermeability, leukocyte adhesion and migration, and cell adhesion molecule expression. In addition, 1 increased the phagocytic activity of macrophages and exhibited bacterial clearance effects in the peritoneal fluid and blood of mice with cecal ligation and puncture-induced sepsis. Collectively, these results suggested that 1 might have potential therapeutic activity against various severe vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway.

Anti-AIDS agents 68. The first total synthesis of a unique potent anti-HIV chalcone from genus Desmos

The first total synthesis of a unique highly functionalized and potent anti-HIV chalcone 1, isolated from genus Desmos, was achieved from commercially available 2,4,6-trihydroxytoluene (3) or 2,4,6-trihydroxybenzaldehyde (2) in five (from 3) or six steps (from 2).

Synthesis of aurentiacin

Aurentiacin 7 has been isolated from Pityrogramma triangularis var. pallida and synthesised from phloroacetophenone 1 in several steps. All the new products have been characterised on the basis of spectral data and micro analysis.

A C-Methylbiflavone from Cephalotaxus harringtonia K. Koch

6-C-Methyl-7-O-methylamentoflavone (1) isolated from the leaves of Cephalotaxus harringtonia K.Koch (Cephalotaxaceae) has been identified on the basis of the spectral data of its hexamethyl ether (1a) and its penta-acetate (1b).The location of the C-methyl group was first deduced from 1H n.m.r. studies with a lanthanide shift reagent and confirmed by a synthesis of the hexamethyl ether (1a).