149681-90-3Relevant academic research and scientific papers
Selective substitution reactions of methoxycarbonylamino-1-(1- benzotriazolyl)alkanes with active methylene compounds
Zhou, Liejin,Lv, Xin,Mao, Hui,Wang, Xiaoxia
scheme or table, p. 434 - 440 (2011/06/17)
Benzotriazole adducts methoxycarbonylamino-1-(1-benzotriazolyl)alkanes 1 were derived from the condensation of an aldehyde, benzotriazole, and methylcarbamate. The leaving tendency of methoxycarbonylamino group (MeOCONH) and benzotriazole group (Bt) was i
Convenient Novel Syntheses of 1,1-Bis(heteroaryl)alkanes
Katritzky, Alan R.,Xie, Linghong,Fan, Wei-Qiang
, p. 4376 - 4381 (2007/10/02)
A variety of symmetrical 1,1-bis(heteroaryl)alkanes are prepared in excellent yields from the reaction of N-(α-benzotriazolylalkyl)carbamate 2 (itself easily available from the condensation of benzotriazole, an aldehyde, and an alkyl carbamate) with an excess of 2-methylthiophene or 2-methylfuran.When methyl N-(α-benzotriazolylalkyl)carbamate 2a is treated with 1 equiv of a heterocycle, the benzotriazolylalkyl-substituted heterocycle is formed.These intermediates react further with other heterocycles to give unsymmetrical 1,1-bis(heteroaryl)alkanes in good yields under mild conditions.
