126200-30-4

Basic information

• Product Name: diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate
• Synonyms: diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate
• CAS NO: 126200-30-4
• Molecular Weight: 367.404
• Mol File: 126200-30-4.mol

Chemical Properties

• CAS DataBase Reference: diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate(126200-30-4)
• EPA Substance Registry System: diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate(126200-30-4)

Safety Data

• Hazardous Substances Data: 126200-30-4(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 100-52-7 benzaldehyde 
• 149681-90-3 methyl (1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methylcarbamate 
• 105-53-3 diethyl malonate 
• 5292-53-5 diethyl benzalmalonate 
• 117067-48-8 1-benzotriazolyl-N-benzoyl-1-phenylmethylamine 
• 120803-36-3 1-morpholino[(phenyl)methyl]benzotriazole 

Relevant articles and documents

Uncatalysed intermolecular aza-Michael reactions

The catalyst-free reactions of activated alkenes with primary and secondary amines were investigated leading to various mono- and di-hydroamination products, the latter being rare and original. These reactions were shown to depend first on the strength of the nucleophile. Temperature and steric hindrance of the reagents were the other key factors controlling the selectivity of these aza-Michael reactions. In spite of their poor nucleophilicities, some N-heterocyclic amines could react with different activated alkenes affording valuable intermediates. Such results tended to demonstrate the hydrogen-bonding interactions between activated alkenes and poly-nitrogen aromatic cycles may control these concerted or fully conjugate aza-Michael additions.

Selective substitution reactions of methoxycarbonylamino-1-(1- benzotriazolyl)alkanes with active methylene compounds

Benzotriazole adducts methoxycarbonylamino-1-(1-benzotriazolyl)alkanes 1 were derived from the condensation of an aldehyde, benzotriazole, and methylcarbamate. The leaving tendency of methoxycarbonylamino group (MeOCONH) and benzotriazole group (Bt) was i

Dy(OTf)3-mediated selective substitution of N-(α-benzotriazolyl-alkyl)amides with active methylene compounds for synthesis of benzotriazole derivatives

A Dy(OTf)3-mediated selective substitution reaction of N-(α-benzotriazolyl-alkyl)amides with active methylene compounds is reported. The present procedure provides a facile method for the synthesis of benzotriazole derivatives.

N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids

N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.