35173-74-1Relevant academic research and scientific papers
Lewis acid-catalyzed reactions in protic media. Lanthanide-catalyzed reactions of indoles with aldehydes or ketones
Chen, Depu,Yu, Libing,Wang, Peng George
, p. 4467 - 4470 (1996)
Lanthanide triflates were found to be effective catalysts for reactions of indoles with aldehydes or ketones in aqueous solution.
Trinuclear Lanthanide Coordination Clusters: Single-Molecule-Magnet Behavior and Catalytic Activity in the Friedel-Crafts Alkylation Reaction
Sarkar, Arijit,Gómez-García, Carlos J.,Benmansour, Samia,Nayek, Hari Pada
, p. 974 - 980 (2019)
A new multidentate ligand (H3L) was synthesized by the condensation reaction of 4-tert-butyl-2,6-diformylphenol and 2-amino-4-nitrophenol. The reaction of the ligand with hydrated lanthanide nitrate produced two isostructural trinuclear coordin
Highly enantioselective Friedel-Crafts reaction of indoles with imines by a chiral phosphoric acid
Kang, Qiang,Zhao, Zhuo-An,You, Shu-Li
, p. 1484 - 1485 (2007)
Highly enantioselective Friedel-Crafts reactions of indoles with imines catalyzed by a chiral phosphoric acid are developed, affording the 3-indolyl methanamine derivatives with up to >99% ee for a wide range of substrates. Copyright
A mild and environmentally friendly scandium(III) trifluoromethanesulfonate-catalyzed synthesis of bis(3′-indolyl)alkanes and bis(3′-indolyl)-1-deoxyalditols
Sato, Shingo,Sato, Toshihiro
, p. 2251 - 2255 (2005)
Bis(3′-indolyl)alkanes and bis(3′-indolyl) derivatives containing a 1-deoxyalditol moiety were synthesized in the presence of 5 mol % of scandium(III) trifluoromethanesulfonate [Sc(OTf)3] in CH 3CN or EtOH-H2O mixture as a
Novel method for synthesis of unsymmetrical bis(indolyl)alkanes catalyzed by ceric ammonium nitrate (CAN) under ultrasonic irradiation
Zeng, Xiao-Fei,Ji, Shun-Jun,Wang, Shun-Yi
, p. 10235 - 10241 (2005)
The reaction of indole with (1H-indol-3-yl)(alkyl) methanol was catalyzed efficiently by ceric ammonium nitrate under ultrasonic irradiation to afford the unsymmetrical bis(indolyl)alkane in good to excellent yields.
N-H...π(indole) intermolecular interactions in 3,3′-benzylidenediindole
Krishna,Velmurugan,Babu,Perumal
, p. 75 - 78 (1999)
In molecules of the title compound, C23H18N2, two indole systems and one phenyl ring are connected through a common C atom. The two indole substituents are mutually orthogonal. We have identified two N - H...π(indole) inte
Solvent-free indoles addition to carbonyl compounds promoted by CeCl 3·7H2O-NaI-SiO2: An efficient method for the synthesis of streptindole
Bartoli, Giuseppe,Bosco, Marcella,Foglia, Gioia,Giuliani, Arianna,Marcantoni, Enrico,Sambri, Letizia
, p. 895 - 900 (2004)
Efficient electrophilic substitution reactions of indoles with various carbonyl compounds proceed easily in solvent-free conditions using CeCl 3·7H2O-NaI-SiO2. system promoter, to afford the corresponding bis(1H-indol-3-yl
Facile access to bis(indolyl)methanes by copper-catalysed alkylation of indoles using alcohols under air
Nguyen, Ngoc-Khanh,Tran, Duc Long,Hung, Tran Quang,Le, Tra My,Son, Nguyen Thi,Trinh, Quang Thang,Dang, Tuan Thanh,Langer, Peter
supporting information, (2021/03/15)
Bis(3-indolyl)methanes (BIM) are important and present in the structure of many alkaloid and bioactive compounds (anti-inflammatory, anticancer, antiobesity, antimicrobial, etc.). Herein, we have reported an air stable and convenient Cu(OAc)2 c
Magnetically recyclable CuFe2O4 catalyst for efficient synthesis of bis(indolyl)methanes using indoles and alcohols under mild condition
Bui, Hoang Yen,Dang, Tuan Thanh,Ha, Minh-Tuan,Hung, Tran Quang,Nguyen, Ngoc-Khanh,Nguyen, Van Tuyen,Tran, Bich Ngoc,Trinh, Quang Thang,Vu, Xuan Hoan
, (2020/11/30)
Bis(3-indolyl)methanes (BIM) are highly valuable and appear in the core structure of many natural products and pharmacologically active compounds (anticancer, anti-inflammatory, antiobesity, antimetastatic, antimicrobial, etc.). Herein, we have disclosed
Phosphine-Free Manganese(II)-Catalyst Enables Acceptorless Dehydrogenative Coupling of Alcohols with Indoles
Yadav, Vinita,Balaraman, Ekambaram,Mhaske, Santosh B.
supporting information, p. 4430 - 4439 (2021/08/03)
Herein, an air-stable, molecularly defined NNN?Mn(II) pincer complex catalyzed acceptorless dehydrogenative coupling of alcohols with indoles is reported. A wide variety of symmetrical and unsymmetrical bis(indolyl)methane derivatives as well as some structurally important products such as Vibrindole A, Turbomycin B alkaloid, Antileukemic, and Anticancer agents were synthesized. Mechanistic studies illustrate the importance of the NH moiety in the complex and the crucial role of metal-ligand cooperation during catalysis. (Figure presented.).
