149703-21-9

Basic information

• Product Name: methyl tosyl-D-phenylalaninate
• Synonyms: methyl tosyl-D-phenylalaninate
• CAS NO: 149703-21-9
• Molecular Weight: 333.408
• Mol File: 149703-21-9.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: methyl tosyl-D-phenylalaninate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl tosyl-D-phenylalaninate(149703-21-9)
• EPA Substance Registry System: methyl tosyl-D-phenylalaninate(149703-21-9)

Safety Data

• Hazardous Substances Data: 149703-21-9(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 17234-07-0 ester methylique de la N,O-ditosyl L-serine 
• 93380-04-2 ester methylique de la N-tosyl β-iodo L-alanine 
• 591-51-5 phenyllithium 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 70-55-3 toluene-4-sulfonamide 
• 104-15-4 toluene-4-sulfonic acid 
• 63-91-2 L-phenylalanine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 67-56-1 methanol 
• 13505-32-3 N-tosyl-(S)-phenylalanine 
• 129397-81-5 methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalaninate 
• 158109-81-0 cis-(2S,3S)-(+)-N-(p-toluenesulfonyl)-2-carbomethoxy-3-phenylaziridine 

Downstream Products

• 82495-70-3 (2S)-2-p-toluenesulfonamido-3-phenylpropanol 
• 1208408-69-8 (R)-2-[(2-benzyloxybenzyl)(toluene-4-sulfonyl)amino]-3-phenylpropionic acid methyl ester 
• 1303530-15-5 2-[(2-bromo-5-methoxybenzyl)(toluene-4-sulfonyl)amino]-3-phenylpropionic acid methyl ester 
• 932725-34-3 (S)-3-benzyl-4-(toluene-4-sulfonyl)-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine 
• 1303530-22-4 N-(1-benzyl-2-hydroxyethyl)-N-(2-bromobenzyl)-4-methylbenzenesulfonamide 
• 1303530-23-5 N-(2-bromo-5-methoxybenzyl)-N-(1-hydroxymethyl-2-phenylethyl)-4-methylbenzenesulfonamide 
• 1303530-25-7 3-benzyl-7-methoxy-4-(toluene-4-sulfonyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine 
• 1303530-14-4 2-[(2-bromobenzyl)(toluene-4-sulfonyl)amino]-3-phenylpropionic acid methyl ester 

Relevant articles and documents

Aqueous MW eco-friendly protocol for amino group protection

In this paper a new catalyst-free and on-water method for protection of amines and amino acids with di-tert-butyl dicarbonate, 9-fluorenylmethoxycarbonyl chloride, acetyl chloride and tosyl chloride is presented. The protection can be realized in a few minutes under microwave-assistance. The reaction proved to be chemoselective in presence of ambident nucleophiles and water solution of di-tert-butyl carboxylic acid or chloride acid are the only wastes produced.

Transition Metal-Free N-Arylation of Amino Acid Esters with Diaryliodonium Salts

A transition metal-free approach for the N-arylation of amino acid derivatives has been developed. Key to this method is the use of unsymmetric diaryliodonium salts with anisyl ligands, which proved important to obtain high chemoselectivity and yields. The scope includes the transfer of both electron deficient, electron rich and sterically hindered aryl groups with a variety of different functional groups. Furthermore, a cyclic diaryliodonium salt was successfully employed in the arylation. The N-arylated products were obtained with retained enantiomeric excess.

Enantioselective vinylation of aldehydes with the vinyl Grignard reagent catalyzed by magnesium complex of chiral BINOLs

Enantioselective vinylation of aldehydes via direct catalytic asymmetric Grignard reaction of aldehdyes and the vinyl Grinard reagent is a long-standing challenge. This work demonstrated that the magnesium (S)-3,3′-dimethyl BINOLate enantioselectively catalyze the direct vinylation of aldehydes with the deactivated vinylmagnesium bromide by bis(2-[N,N′-dimethylamino]ethyl) ether (BDMAEE) in the addition of n-butylmagnesium chloride. The highest ee of 63% was achieved up to date.

Preparation method of polysubstituted pyrrole compound

The invention discloses a preparation method of a polysubstituted pyrrole compound. The preparation method comprises steps as follows: an alkyne enamine compound is subjected to a cyclization reactionunder the catalytic action of univalent gold, a product