149715-45-7 Usage
General Description
(S)-4-benzyl-2-hydroxymethylpiperazine is a chemical compound that belongs to the class of piperazine derivatives. It is a chiral compound, and its specific stereochemistry is denoted by the prefix "(S)". (S)-4-benzyl-2-hydroxymethylpiperazine contains a benzyl group and a hydroxymethyl group attached to a piperazine ring. Piperazine derivatives have been studied for their potential pharmacological activities, including as antiviral, antipsychotic, and antihistaminic agents. The specific properties and potential uses of (S)-4-benzyl-2-hydroxymethylpiperazine depend on its stereochemistry and structural features, and further research is needed to fully understand its potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 149715-45-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,7,1 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 149715-45:
(8*1)+(7*4)+(6*9)+(5*7)+(4*1)+(3*5)+(2*4)+(1*5)=157
157 % 10 = 7
So 149715-45-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O/c15-10-12-9-14(7-6-13-12)8-11-4-2-1-3-5-11/h1-5,12-13,15H,6-10H2/t12-/m0/s1
149715-45-7Relevant articles and documents
COMPOUNDS THAT INHIBIT MCL-1 PROTEIN
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, (2018/10/25)
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (I), or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
Enantiomerically pure 2-piperazinemethanols as novel chiral ligands of oxazaborolidine catalysts in enantioselective borane reductions
Inoue, Tsutomu,Sato, Daisuke,Komura, Kenichi,Itsuno, Shinichi
, p. 5379 - 5382 (2007/10/03)
Novel enantiomerically pure 2-piperazinemethanols (3-5) were synthesized from 2-piperazinecarboxylic acid 1. The asymmetric reduction of aromatic ketones, ketimine and oxime ether has been performed with reagents prepared from 2-piprazinemethanol and borane to yield enantiomerically enriched alcohols and amines, respectively. The preferred absolute configuration of the product was dependent on the structure of the sulfonyl substituent in the chiral ligand.
