15000-00-7

Usage

Usage as an antioxidant

Food and food packaging BHA prevents rancidity and increases the shelf-life of food products by neutralizing free radicals.

Application in cosmetic and pharmaceutical products

Antioxidant properties BHA helps protect these products from oxidation, ensuring their stability and efficacy.

Potential therapeutic effects

Anti-inflammatory BHA has been studied for its ability to reduce inflammation in the body.

Potential therapeutic effects

Anti-cancer Research has explored the possibility of BHA having cancer-fighting properties.

Controversy over safety

High doses and health risks Some concerns exist regarding the safety of BHA, as high doses have been associated with potential health risks.

Versatility

Industrial and potential therapeutic applications 2-(1-hydroxy-1-methyl-ethyl)-4-methoxy-phenol has a range of uses in various industries and holds promise for therapeutic benefits.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 52249-86-2 2-benzyloxy-4-methoxyacetophenone 
• 2905-82-0 methyl 5-methoxy-2-hydroxybenzoate 
• 2612-02-4 5-methoxysalicylic acid 
• 917-54-4 methyllithium 
• 705-15-7 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one 
• 676-58-4 methylmagnesium chloride 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 936716-94-8 C₁₉H₂₂O₃ 
• 865305-37-9 2-isopropyl-4-methoxy-5-nitro-phenol 
• 865305-38-0 2-isopropyl-4-methoxy-3-nitro-phenol 
• 865305-35-7 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-5-nitro-phenyl ester 
• 865305-36-8 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-3-nitro-phenyl ester 
• 865305-33-5 5-(5-amino-2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 
• 865305-41-5 5-(2-isopropyl-5-isothiocyanato-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 
• 865305-40-4 4-chloro-N-[5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]butyramide 
• 865305-39-1 (2-isopropyl-4-methoxy-5-nitro-phenoxy)-acetonitrile 
• 865305-34-6 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-phenyl ester 
• 13522-86-6 2-iso-propyl-4-methoxyphenol 

Relevant academic research and scientific papers

METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS

Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more diseases or conditions selected from the group consisting of hypertension, heart failure, dyspnea, and

Methods of Using Diaminopyrimidine P2X3 and P2X 2/3 Receptor Modulators for Treatment of Acute and Sub-Acute Cough, Urge to Cough and Chronic Cough, in Respiratory Diseases

Methods for treating cough, chronic cough and urges to cough associated with respiratory diseases with a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of Formu

Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X3/P2X2/3 antagonist for the treatment of pain

The purinoceptor subtypes P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions. Identification of a potent and selective dual P2X3/P2X2/3 diaminopyrimidine antagonist RO-4

Diaminopyrimidines as P2X3 and P2X2/3 modulators

Compounds of formula (I): wherein R1 and R2 are as defined herein. Also disclosed are methods of making and using the subject compounds.

Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases

Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Novel photolabile protecting group for carbonyl compounds

Equation presented A novel type of photo-protecting group for carbonyl compounds is described. The protecting group is readily accessed in one step from commercially available material. Installation of the protecting group upon the carbonyl compounds is achieved in excellent yields. The carbonyl compounds in their protected form are remarkably stable under various conditions and can be released photochemically in high efficiency.

Process for synthesis of phenoxy diaminopyrimidine derivatives

A method for preparing a compound of formula I the method comprising treating a compound of formula d with an iodination reagent, to form the compound of formula I, wherein R1, R2 and R3 are as defined herein.

Diaminopyrimidines as P2X3 and P2X2/3 antagonists

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.