13522-86-6

Basic information

• Product Name: 2-ISOPROPYL-4-METHOXYPHENOL
• Synonyms: 2-ISOPROPYL-4-METHOXYPHENOL;PHENOL, 4-METHOXY-2-(1-METHYLETHYL)-;EOS-61048
• CAS NO: 13522-86-6
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol File: 13522-86-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 263 °C at 760 mmHg
• Flash Point: 113.6 °C
• Appearance: /
• Density: 1.026 g/cm³
• PKA: 10.97±0.18(Predicted)
• CAS DataBase Reference: 2-ISOPROPYL-4-METHOXYPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ISOPROPYL-4-METHOXYPHENOL(13522-86-6)
• EPA Substance Registry System: 2-ISOPROPYL-4-METHOXYPHENOL(13522-86-6)

Safety Data

• Hazardous Substances Data: 13522-86-6(Hazardous Substances Data)

Usage

General Description

2-Isopropyl-4-methoxyphenol, also known as propofol, is a chemical compound used as a general anesthetic in medical settings. It is a white, crystalline substance that is insoluble in water but soluble in organic solvents. Propofol works by enhancing the activity of gamma-aminobutyric acid (GABA) in the brain, leading to sedation and anesthesia. It is often used for the induction and maintenance of anesthesia during surgeries and medical procedures. However, it can also cause side effects such as respiratory depression, hypotension, and pain upon injection. Despite its potential drawbacks, propofol is a widely used and important tool in anesthetic care.

Upstream product

• 88-69-7 2-(1-methylethyl)phenol 
• 26307-50-6 4-bromo-2-isopropyl-phenol 
• 187737-37-7 propene 
• 150-76-5 4-methoxy-phenol 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 705-15-7 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one 
• 6295-35-8 6-methoxy-4-methyl-chromen-2-one 
• 676-58-4 methylmagnesium chloride 
• 15000-00-7 2-(1-hydroxy-1-methyl-ethyl)-4-methoxy-phenol 
• 2349-71-5 2-isopropylhydroquinone 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 865305-34-6 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-phenyl ester 
• 865305-39-1 (2-isopropyl-4-methoxy-5-nitro-phenoxy)-acetonitrile 
• 865305-40-4 4-chloro-N-[5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]butyramide 
• 865305-41-5 5-(2-isopropyl-5-isothiocyanato-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 
• 865305-33-5 5-(5-amino-2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 
• 114650-46-3 2-isopropyl-4-methoxyaniline 
• 927872-64-8 2-(2-isopropyl-4-methoxyphenoxy)acetonitrile 
• 865304-71-8 5-(2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 
• 865305-37-9 2-isopropyl-4-methoxy-5-nitro-phenol 
• 865305-38-0 2-isopropyl-4-methoxy-3-nitro-phenol 
• 865305-35-7 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-5-nitro-phenyl ester 
• 865305-36-8 toluene-4-sulfonic acid 2-isopropyl-4-methoxy-3-nitro-phenyl ester 

Relevant articles and documents

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NOVEL PROCESS FOR SYNTHESIS OF A PHENOXY DIAMINOPYRIMIDINE COMPOUND

Disclosed herein is a novel process for preparing Compound A free base, 5-((2,4-diaminopyrimidin-5-yl)oxy)-4-isopropyl-2-methoxybenzenesulfonamide, and a citrate salt of Compound A with simplified chemistry and a high overall yield: Compound A. In one emb

METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS

Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more diseases or conditions selected from the group consisting of hypertension, heart failure, dyspnea, and