15000-41-6

Basic information

• Product Name: 3-benzyl-2-hydroxyquinolin-4(1H)-one
• Synonyms: 2(1H)-Quinolinone, 4-hydroxy-3-(phenylmethyl)-; 3-Benzyl-2,4-quinolinediol; 3-benzyl-4-hydroxy-1,2-dihydroquinolin-2-one; 3-Benzyl-4-hydroxy-1H-quinolin-2-one; 3-Benzyl-4-hydroxyquinolin-2(1H)-one
• CAS NO: 15000-41-6
• Molecular Formula: C₁₆H₁₃NO₂
• Molecular Weight: 251.2799
• Mol File: 15000-41-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 426°C at 760 mmHg
• Flash Point: 211.4°C
• Density: 1.299g/cm³
• Vapor Pressure: 5.13E-08mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: 3-benzyl-2-hydroxyquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-hydroxyquinolin-4(1H)-one(15000-41-6)
• EPA Substance Registry System: 3-benzyl-2-hydroxyquinolin-4(1H)-one(15000-41-6)

Safety Data

• Hazardous Substances Data: 15000-41-6(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 616-75-1 2-benzylmalonic acid 
• 58013-72-2 3-benzyl-3-chloroquinoline-2,4(1H,3H)-dione 
• 607-81-8 diethyl 2-benzylmalonate 
• 100-52-7 benzaldehyde 
• 146765-17-5 3-amino-3-benzylquinoline-2,4(1H,3H)-dione 
• 70254-43-2 4-Hydroxy-2-quinolone 
• 100-51-6 benzyl alcohol 
• 134-20-3 2-carbomethoxyaniline 
• 2985-39-9 2-benzylmalonic acid monoethyl ester 
• 87-25-2 2-ethoxycarbonylaniline 
• 29425-06-7 benzylmalonyl dichloride 
• 92859-63-7 3-benzyl-3-bromoquinoline-2,4(1H,3H)-dione 
• 144603-93-0 3-azido-3-benzylquinoline-2,4(1H,3H)-dione 

Downstream Products

• 70611-42-6 3-Benzoyl-3-benzyl-1,2,3,4-tetrahydro-chinolin-2,4-dion 
• 70611-43-7 4-Benzoyloxy-3-benzyl-1,2-dihydro-chinolin-2-on 
• 110229-57-7 4-Benzylamino-3-benzyl-2(1H)-chinolon 
• 62668-79-5 3-benzyl-4-hydroxy-6H-pyrano[3,2-c]quinoline-2,5-dione 
• 26386-86-7 3-hydroxyquinolin-2(1H)-one 
• 1432733-35-1 3-benzyl-1,2-dihydro-2-oxoquinolin-4-yl dihydrogen phosphate 
• 144603-93-0 3-azido-3-benzylquinoline-2,4(1H,3H)-dione 
• 144603-57-6 3-Benzyl-3-fluoro-1H-quinoline-2,4-dione 
• 157027-52-6 C₃₄H₂₆ClN₂P 
• 157027-35-5 4-Azido-3-benzyl-2-chloro-quinoline 
• 110216-88-1 4-amino-3-benzyl-2(1H)-quinolone 
• 477950-01-9 3-benzyl-3-benzylaminoquinoline-2,4-(1H,3H)-dione 
• 477949-99-8 3-benzyl-3-butylaminoquinoline-2,4-(1H,3H)-dione 

Relevant articles and documents

4-HYDROXY-2-QUINOLONES. 1. EFFICIENT METHOD FOR OBTAINING 3-ALKYL-4-HYDROXY-2-QUINOLONES

3-Alkyl-4-hydroxy-2-quinolones were obtained in high yields via the Dieckmann intramolecular condensation of substituted malonic acid ethyl ester 2-carbalkoxyanilides.

Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones

3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position

Stereochemistry of the reduction of α-chloroketones with sodium borohydride—application to 3-chloroquinoline-2,4-diones: Dedicated to the memory of Professor Dr.?Vojeslav ?těrba who died in September 2015 being nearly 93 years old

3-Chloroquinoline-2,4-diones were reduced with sodium borohydride to give syn- and anti-chlorohydrins, the stereochemistry of which was established by NMR spectroscopy. Both stereoisomeric chlorohydrins were reacted with potassium carbonate in methanol. a