15001-71-5

Usage

Uses

Used in Food Industry:
Propanoic acid, 2-ethoxy-2-methyl is used as a flavoring agent for its fruity odor, enhancing the taste and aroma of various food products.
Used in Perfume Production:
This chemical compound is utilized in the production of perfumes, where its fruity scent contributes to the creation of various fragrances.
Used as a Solvent in Industrial Processes:
Propanoic acid, 2-ethoxy-2-methyl serves as a solvent in a range of industrial applications, facilitating processes that require a safe and low toxicity chemical for dissolving or suspending other substances.

InChI:InChI=1/C6H12O3/c1-4-9-6(2,3)5(7)8/h4H2,1-3H3,(H,7,8)

Upstream product

• 64-17-5 ethanol 
• 2052-01-9 2-bromo-2-methylpropionic acid 
• 6957-89-7 Ethyl dichloro-(ethoxy)-acetate 
• 17860-41-2 2-ethoxy-2-methylpropanoic acid methyl ester 
• 76474-10-7 2-ethoxyisobutyronitrile 
• 141-52-6 sodium ethanolate 
• 151598-88-8 ethyl 2-ethoxy-2-methylpropanoate 
• 1000296-72-9 α-ethoxy-isobutyric acid benzyl ester 

Downstream Products

• 151598-88-8 ethyl 2-ethoxy-2-methylpropanoate 
• 97-63-2 methyl methacrylate 
• 1000296-74-1 chloromethyl 2-ethoxy-2-methylpropanoate 
• 17860-09-2 4-Chloro-benzene-1,3-disulfonic acid 3-amide 1-[(2-ethoxy-2-methyl-propyl)-methyl-amide] 
• 1263101-72-9 C₈H₁₅ClO₃S 
• 1575817-60-5 4-chloro-N-(1-((1-(2-cyano-4-ethoxy-4-methylpent-2-enoyl)pyrrolidin-2-yl)methyl)-5-(((S)-3,3-dimethylbutan-2-ylamino)methyl)-1H-benzo[d]imidazol-2-yl)benzamide 
• 1575819-81-6 tert-butyl (2-(4-chlorobenzamido)-1-((1-(2-cyano-4-ethoxy-4-methylpent-2-enoyl)pyrrolidin-2-yl)methyl)-1H-benzo[d]imidazol-5-yl)methyl((S)-3,3-dimethylbutan-2-yl)carbamate 
• 130797-57-8 2-ethoxy-2-methylpropanal 

Relevant academic research and scientific papers

BENZIMIDAZOLE DERIVATIVES AS RLK and ITK INHIBITORS

The present disclosure is directed to certain inhibitors of RLK and ITK of formula (I), pharmaceutical compositions comprising such compounds, and method of treating diseases mediated by inhibition of RLK and ITK.

N-Acyl-N'-(pyridin-2-yl) Ureas and Analogs Exhibiting Anti-Cancer and Anti-Proliferative Activities

Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.

BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS

The present disclosure is directed to certain inhibitors of kinases such as ITK, BLK, BMX, BTK, JAK3, TEC, TXK, HER2 (ERBB2), or HER4 (ERBB4), in particular ITK, pharmaceutical compositions comprising such compounds, and method of treating diseases mediated by such kinases.

Development of a practical and efficient synthesis of chloromethyl 2-ethoxy-2-methylpropanoate

An efficient synthesis of chloromethyl 2-ethoxy-2-methylpropanoate from 2-bromoisobutyric acid is reported. Four developments were key to this route: (i) a mild, base-mediated ethanolysis of a tertiary alkyl bromide, (ii) a sodium bisulfite purge of 2-methylacrylic acid, (iii) preparation of a thiomethyl ester via a formal Pummerer process with DMSO, and (iv) improved conversion of a thiomethyl ester to a chloromethyl ester through suppression of a competing chlorination pathway.

Grafting and coloring onto silver nanoparticles by photoinduced surface modification

(Figure Presented) Surface modification of metal nanostructures can create multifunctional materials potentially very useful in many application fields and, consequently, has been the subject of intensive studies. This work reported the modification of silver nanoparticles (Ag NPs) by UV-induced interface reactions, a method controllable in both the color and the surface chemistry of the nanoparticles. Using poly(N-vinyl-2-pyrrolidone) (PVP) as the protecting polymer, Ag NPs were synthesized in ethanol and then mixed with F-bromoisobutyric acid (BIBA). When the mixture is exposed to UV irradiation, Ag NPs present themselves in a serial tone from pale blue to blue, dark blue, and finally purple with the progress of the interface reactions. It is shown that these color changes are directly related to the chemical components on the surface of Ag NPs, and hence the correlation of the colors with the chemical states of main components on the surface of Ag NPs has been made during the course of interface reactions.

PENEM PRODRUGS

Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.

Mass Spectrometry of 2-Alkylthio-2-methylpropanoic Acids and Their Esters and Amides. Structural and Steric Effects on the McLafferty Rearrangement

The electron ionization mass spectra (MS) of S-methylated derivatives of N-(2-mercapto-2-methylpropanoyl)-L-cysteine and 2-alkylthio-2-methylpropanoic acids, as well as their esters and amides, were examined.Use of the deuterium labeling technique and accurate mass measurement supported the proposed fragmentation pathways.Extensive loss of CH2S from a molecular ion by the McLafferty rearrangementof a primary hydrogen is important in the MS of S-methyl compounds of amide derivatives.It was demonstrated that the intensity of the rearrangement ion decreases in the order of amide, ester, and acid, and in the case if amides the reaarangement is suppressed by the nonbonded interaction between methyl groups on the α carbon and the amide nitrogen.Keywords-N-(2-mercapto-2-methylpropanoyl)-L-cysteine; 2-alkylthio-2-methylpropanoic acid and methyl ester; 2-alkylthio-2-methylpropanamide; electron impact mass spectrometry; McLafferty rearrangement; steric interaction