1505-62-0

Basic information

• Product Name: 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID
• Synonyms: 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID;AKOS B018461;ART-CHEM-BB B018461;5-Methylbenzo[b]thiophene-2-carboxylic acid
• CAS NO: 1505-62-0
• Molecular Formula: C₁₀H₈O₂S
• Molecular Weight: 192.23
• Mol File: 1505-62-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 218.0-219.5 °C
• Boiling Point: 386.1 °C at 760 mmHg
• Flash Point: 187.3 °C
• Appearance: /
• Density: 1.355 g/cm³
• Vapor Pressure: 1.18E-06mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: 2-8°C
• PKA: 3.52±0.30(Predicted)
• CAS DataBase Reference: 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID(1505-62-0)
• EPA Substance Registry System: 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID(1505-62-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 1505-62-0(Hazardous Substances Data)

Usage

General Description

5-Methyl-1-benzothiophene-2-carboxylic acid is a chemical compound belonging to the class of benzothiophenes. It is a carboxylic acid derivative with a methyl group attached to the 5-position of the benzothiophene ring. 5-METHYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID has potential applications in the pharmaceutical and agrochemical industries, as it can be used as an intermediate in the synthesis of various bioactive molecules and pesticides. It is also used as a building block in the production of organic compounds with diverse therapeutic and pesticidal properties. Additionally, 5-Methyl-1-benzothiophene-2-carboxylic acid may exhibit certain biological activities, which make it a target for further research and development in medicinal chemistry and chemical biology.

InChI:InChI=1/C10H8O2S/c1-6-2-3-8-7(4-6)5-9(13-8)10(11)12/h2-5H,1H3,(H,11,12)

Upstream product

• 13616-73-4 5-methyl-2-methylthiobenzaldehyde 
• 14315-14-1 5-methylthianaphthene 
• 124-38-9 carbon dioxide 
• 82787-69-7 5-methylbenzothiophene-2-carboxylic acid methyl ester 
• 93249-44-6 2-fluoro-5-methylbenzaldehyde 
• 101219-39-0 ethyl 5-methylbenzo[b]thiophene-2-carboxylate 
• 2046-77-7 2-acetyl-5-methylbenzo[b]thiophene 

Downstream Products

• 14315-14-1 5-methylthianaphthene 
• 82787-69-7 5-methylbenzothiophene-2-carboxylic acid methyl ester 
• 852668-51-0 C₂₄H₂₄N₄O₃S 
• 82788-51-0 5-Imidazol-1-ylmethyl-benzo[b]thiophene-2-carboxylic acid 
• 82787-71-1 5-(1-imidazolylmethyl)benzo[b]thiophene-2-carboxylic acid methyl ester 
• 82787-70-0 methyl 5-(bromomethyl)benzo[b]thiophene-2-carboxylate 

Relevant articles and documents

SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

Provided herein are compounds and compositions useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.

GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7- nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

Benzimidazole derivatives

A benzimidazole derivative or its medically acceptable salt, represented by the following formula (1), that is a human chymase activity inhibitor capable of being applied clinically: 1wherein, R1 and R2 represent a hydrogen atom, an alkyl group or an alkoxy group, etc., A represents an alkylene group or an alkenylene group, E represents —COOR3, —SO3R3, —CONHR3 or —SO2NHR3, etc., G represents an alkylene group, M represents a single bond or —S(O)m. J represents a heterocyclic group, and X represents —CH= or a nitrogen atom.