150639-15-9 Usage
Uses
Used in Organic Synthesis:
(1s,3s)-3-phenylcyclobutanol is utilized as an intermediate in organic synthesis for the production of various complex organic molecules. Its unique structure and chirality make it a valuable building block for the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1s,3s)-3-phenylcyclobutanol is employed as a key component in the development of new drugs. Its chiral nature allows for the exploration of the different biological activities of its enantiomers, potentially leading to the discovery of more effective and selective therapeutic agents.
Used in Chiral Compound Research:
(1s,3s)-3-phenylcyclobutanol serves as a model compound for studying the properties and behavior of chiral molecules. Understanding the interactions between its enantiomers and biological targets can provide insights into the design of enantioselective catalysts and the development of enantiomerically pure compounds with specific therapeutic effects.
Used in Pharmaceutical Industry:
(1s,3s)-3-phenylcyclobutanol is used as an active pharmaceutical ingredient (API) in the development of new medications. Its unique structural features and chirality can contribute to the creation of drugs with improved efficacy, selectivity, and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, (1s,3s)-3-phenylcyclobutanol is employed as a precursor for the synthesis of chiral pesticides and other agrochemicals. Its enantiomers may exhibit different levels of activity against pests and diseases, allowing for the development of more effective and environmentally friendly products.
Check Digit Verification of cas no
The CAS Registry Mumber 150639-15-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,6,3 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 150639-15:
(8*1)+(7*5)+(6*0)+(5*6)+(4*3)+(3*9)+(2*1)+(1*5)=119
119 % 10 = 9
So 150639-15-9 is a valid CAS Registry Number.
150639-15-9Relevant articles and documents
Stereoselective reduction of N-(3-arylcyclobutylidene)amines
Verniest, Guido,Claessens, Sven,De Kimpe, Norbert
, p. 3299 - 3302 (2006)
N-Alkylimines derived from cyclobutanones have not been evaluated in depth as building blocks for organic synthesis, although these compounds are, among others, good precursors for interesting 3-arylcyclobutylamines. The reduction of various N-alkyl-N-(3-
Synthesis and Physicochemical Properties of 3-Fluorocyclobutylamines
Chernykh, Anton V.,Radchenko, Dmytro S.,Chernykh, Alla V.,Kondratov, Ivan S.,Tolmachova, Nataliya A.,Datsenko, Olexandr P.,Kurkunov, Maxim A.,Zozulya, Sergey X.,Kheylik, Yuri P.,Bartels, Katharina,Daniliuc, Constantin G.,Haufe, Günter
, p. 6466 - 6471 (2015/10/19)
Hitherto unknown cis- and trans-3-alkyl- and 3-aryl-3-fluorocycobutylamines have been synthesised selectively from 3-oxocyclobutane carboxylic acid in six or seven steps. Comparison of their pKa and logD values with those of the fluorine-free p
Stereoselective Synthesis of 3-Substituted Cyclobutanols and Products Derived Therefrom
Dehmlow, Eckehard V.,Bueker, Sabine
, p. 2759 - 2764 (2007/10/02)
3-Substituted cyclobutanones 2 are prepared by alkene/dichloroketene cycloadditions and subsequent dehalogenation.Reduction with LiAlH(OtBu)3 furnishes cis-cyclobutanols 3 in 95-100percent selectivity.Mitsunobu inversion turned out to be the only practica
Substituent effects on cyclobutyl and cyclopropylcarbinyl cations
Wiberg, Kenneth B.,Shobe, David,Nelson, Gordon L.
, p. 10645 - 10652 (2007/10/02)
The acetolyses of 3-substituted cyclobutyl tosylates (X = Ar, Cl, and OEt) were examined giving rate constants and product distributions. With the alkyl- and aryl-substituted compounds, the rate-determining step leads to the formation of a bridged cyclobu