150681-19-9Relevant articles and documents
Tolvaptan-Type Vasopressin Receptor Ligands: Important Role of Axial Chirality in the Active Form
Tabata, Hidetsugu,Yoneda, Tetsuya,Oshitari, Tetsuta,Takahashi, Hideyo,Natsugari, Hideaki
, p. 4503 - 4509 (2017/06/05)
The anti and syn isomers of tolvaptan-type compounds, N-benzoyl-5-hydroxy-1-benzazepines (5a-c), were prepared in a stereocontrolled manner by biasing the conformation with a methyl group at C9 and C6, respectively, and the enantiomeric forms were separat