150698-74-1

Usage

Uses

Used in Pharmaceutical Industry:
3'-BROMO-4',2,2,2-TETRAFLUOROACETOPHENONE 98 is used as a key intermediate in the synthesis of various pharmaceuticals for its strong electrophilic properties, which facilitate the formation of new chemical bonds and the development of novel drug candidates.
Used in Agrochemical Industry:
3'-BROMO-4',2,2,2-TETRAFLUOROACETOPHENONE 98 is used as a crucial building block in the production of agrochemicals, contributing to the development of innovative and effective crop protection solutions.
Used in Fine Chemicals Industry:
3'-BROMO-4',2,2,2-TETRAFLUOROACETOPHENONE 98 is utilized as an intermediate in the synthesis of fine chemicals, enabling the creation of specialty products with specific applications in various industries.
It is important to handle 3'-BROMO-4',2,2,2-TETRAFLUOROACETOPHENONE 98 with care, as it can be harmful if not properly used and stored.

Upstream product

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Relevant academic research and scientific papers

Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

Diversity-oriented approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH-, and CF3(SCF3)CH-substituted arenes from 1-(Diazo-2,2,2-trifluoroethyl)arenes

Arenes substituted with perfluoroalkyl groups are attractive targets for drug and agrochemical development. Exploiting the carbenic character of donor/acceptor diazo compounds, a diversity-oriented synthesis of perfluoroalkylated arenes, for late stage fluorofunctionalization, is described. The reaction of 1-(diazo-2,2,2-trifluoroethyl)arenes with HF, F/Br, F2, CF3H, and CF3SH sources give direct access to a variety of perfluoroalkyl-substituted arenes presenting with incremental fluorine content. The value of this approach is also demonstrated for radiochemistry and positron emission tomography with the [18F]-labeling of CF3CHF-, CF3CBrF-, and CF3CF2-arenes from [18F]fluoride.

Process for preparing trifluoromethyl ketones

A process is described for preparing trifluoromethyl ketones of the formula I STR1 where R has the given meanings, wherein an alcohol of the formula II STR2 is reacted with a compound of the formula IV where n has the given meaning.