150800-39-8

Upstream product

• 932-22-9 4,5-dichloro-2H-pyridazin-3-one 
• 13484-37-2 1-[2-phenoxyethyl]piperazine 
• 153276-34-7 4-chloro-5-(piperazin-1-yl)-2,3-dihydropyridazin-3-one 
• 622-86-6 2-chloroethoxybenzene 

Relevant academic research and scientific papers

Novel and highly selective postsynaptic α-adrenoreceptor antagonists: Synthesis and structure-activity relationships of alkane-bridged [4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones

The synthesis of selected 4-[4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones and alkane-bridged dimers of 4-, 5- and 6-[4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones is reported. The blocking activity of these compounds was deterrnined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.

New pyridazinones: Synthesis and correlation between structure and α-blocking activity

The synthesis of a series of 5-(4-piperazinyl)-3(2H)-pyridazinone has been reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.