153276-34-7

Basic information

• Product Name: 4-chloro-5-piperazin-1-ylpyridazin-3(2H)-one
• Synonyms: 4-chloro-5-piperazin-1-ylpyridazin-3(2H)-one;AKOS BBV-002064;OTAVA-BB 1180862;4-Chloro-5-piperazin-1-yl-2H-pyridazin-3-one
• CAS NO: 153276-34-7
• Molecular Formula: C₈H₁₁ClN₄O
• Molecular Weight: 214.655
• Mol File: 153276-34-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-5-piperazin-1-ylpyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-5-piperazin-1-ylpyridazin-3(2H)-one(153276-34-7)
• EPA Substance Registry System: 4-chloro-5-piperazin-1-ylpyridazin-3(2H)-one(153276-34-7)

Safety Data

• Hazardous Substances Data: 153276-34-7(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 932-22-9 4,5-dichloro-2H-pyridazin-3-one 

Downstream Products

• 159430-52-1 5-(1-piperazinyl)-3(2H)-pyridazinone 
• 150800-39-8 4-chloro-5-<4-(2-phenoxyethyl)-1-piperazinyl>-3(2H)-pyridazinone 
• 153276-40-5 4-chloro-5-<4-(2-methoxyphenoxyethyl)-1-piperazinyl>-3(2H)-pyridazinone 

Relevant articles and documents

PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

New pyridazinones: Synthesis and correlation between structure and α-blocking activity

The synthesis of a series of 5-(4-piperazinyl)-3(2H)-pyridazinone has been reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.