15090-26-3

Usage

Uses

Used in Chemical Synthesis:
Propanoic acid, 3-(methoxymethylphosphinyl)-, methyl ester is used as a key intermediate in the synthesis of enantiomers of Phoshinothricin, also known as Glufosinate Ammonium (G596950). This herbicide is widely utilized in plant molecular biology and plant tissue culture for various purposes, including the selection of transformed cells and the control of unwanted plant growth.
Used in Plant Molecular Biology:
In the field of plant molecular biology, Propanoic acid, 3-(methoxymethylphosphinyl)-, methyl ester plays a crucial role in the development of herbicide-resistant plants. By synthesizing the enantiomers of Glufosinate Ammonium, Propanoic acid, 3-(methoxymethylphosphinyl)-, methyl ester contributes to the advancement of genetic engineering techniques that enable the creation of plants with enhanced resistance to specific herbicides, thus improving crop yield and reducing the impact of weeds on agricultural productivity.
Used in Plant Tissue Culture:
Propanoic acid, 3-(methoxymethylphosphinyl)-, methyl ester is also employed in plant tissue culture for the selection and propagation of transformed cells. The synthesized enantiomers of Glufosinate Ammonium can be used as selective agents in tissue culture media, allowing for the identification and isolation of cells that have successfully incorporated the desired genetic traits. This process is essential for the development of new plant varieties with improved characteristics, such as higher yield, better disease resistance, and enhanced nutritional content.

Upstream product

• 292638-85-8 acrylic acid methyl ester 
• 756-79-6 dimethyl methane phosphonate 
• 15090-24-1 3-(methylchlorophosphoryl)propionyl chloride 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 

Downstream Products

• 15090-23-0 2-carboxyethyl-methyl-phosphinic acid 

Relevant academic research and scientific papers

Synthesizing method of 3-(alkoxy methyl phosphoryl) propionic ester, analogue and phosphinothricin

The invention discloses a synthesizing method of 3-(alkoxy methyl phosphoryl) propionic ester, analogue and phosphinothricin. The method is characterized in that 3-(methyl halogenated phosphoryl) propionyl halide is used as raw material, the 3-(methyl hal

4 - (hydroxy-(methyl) phosphinyl) - 2-oxo-butyric acid production process

The invention discloses a preparation method of 4-(hydroxy-(methyl)phosphinyl)-2-oxobutyric acid. The preparation method comprises following steps: synthesis of methylphosphoric dichloride; recovery of diethyl phthalate, synthesis of methyl chloro phosphinic propionyl chloride; synthesis of methoxyl methyl phosphinic methyl propionate; synthesis of 4-(hydroxy-(methyl)phosphinyl)-2-oxobutyric acid; and post treatment. Technology processes of the preparation method are simple; yield is high; production cost is low; and production technology is clean. In addition, when 4-(hydroxy-(methyl)phosphinyl)-2-oxobutyric acid obtained by the preparation method is used for synthesis of weed killer glufosinate-ammonium, levo glufosinate-ammonium with high weed killing function is obtained, so that weed killing effect of glufosinate-ammonium is improved greatly.

Process for the preparation of phosphino compounds

Process for the preparation of phosphino compounds Phosphorus-containing compounds of the formula (I) in which R1 and R2 are alkyl, alkoxy or optionally substituted phenyl, R3 and R5 are H, R, optionally substituted phenyl, ROCO--, RO--CO--RO--, halogen, CN, RO--, RO--RO--R-CO--, H2 NCO--, RNHCO-- or RRNCO--, in which R is alkyl, R4 and R6 have the same meaning as defined for R1 and R2 or are a divalent radical in which R7 is oxygen, NR* or sulfur, and R* is H, optionally substituted phenyl or alkyl, are precursors for plant protection agents and fire retardants. According to the invention they can be prepared in high yields and high purity by reacting a compound (R1)(R2)P--OR8, in which R8 is alkyl or optionally substituted phenyl, with an alkene of the formula R3 R4 C=CR5 R6 and at least an equimolar amount of aprotic organic substance such as alcohols, amines, phenols, thiophenols or anilines.