151259-49-3

Upstream product

• 75334-99-5 2,2-Dimethoxy-2-(4-methoxyphenyl)essigsaeure-methylester 
• 70-55-3 toluene-4-sulfonamide 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 

Downstream Products

• 42718-22-9 N-[(methoxycarbonyl)(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Diphenylsilane Reduction of C=O and C=N Bearing Electron-Withdrawing Group in the Presence of Aluminium(III) Chloride

Several α-keto esters and methyl N-p-tolylsulfonyl-2-aryl-2-iminoacetates were reduced to the corresponding α-hydroxy esters and methyl N-p-tolylsulfonyl-2-arylglycinates in high yields by a combination of aluminium(III) chloride and diphenylsilane under operating conditions in which diphenylsilane was added to the pre-formed substrate-aluminium(III) chloride complex in dichloromethane and the mixture stirred.The case of an exactly equivalent amount of aluminium(III) chloride as the substrate resulted in good results.