42718-22-9

Upstream product

• 75334-99-5 2,2-Dimethoxy-2-(4-methoxyphenyl)essigsaeure-methylester 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 13150-76-0 N-[(4-methylphenyl)sulfonyl]-S,S-diphenyl-sulfilimine 
• 70-55-3 toluene-4-sulfonamide 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 
• 151259-49-3 methyl N-p-tolylsulfonyl-2-imino-2-(p-methoxyphenyl)acetate 

Relevant academic research and scientific papers

Metal-Free Benzylic C?H Amination via Electrochemically Generated Benzylaminosulfonium Ions

Electrochemical oxidation of toluene derivatives in the presence of N-tosyldiphenylsulfilimine gave the corresponding benzylaminosulfonium ions, which were treated with tetrabutylammonium iodide under non-electrolytic conditions to give N-tosylbenzylamines. The transformation serves as a metal- and chemical-oxidant-free method for benzylic C?H amination. Because of high oxidation potential of N-tosyldiphenylsulfilimine the present method can be applied to synthesis of various benzylamines from functionalized toluene derivatives.

Diphenylsilane Reduction of C=O and C=N Bearing Electron-Withdrawing Group in the Presence of Aluminium(III) Chloride

Several α-keto esters and methyl N-p-tolylsulfonyl-2-aryl-2-iminoacetates were reduced to the corresponding α-hydroxy esters and methyl N-p-tolylsulfonyl-2-arylglycinates in high yields by a combination of aluminium(III) chloride and diphenylsilane under operating conditions in which diphenylsilane was added to the pre-formed substrate-aluminium(III) chloride complex in dichloromethane and the mixture stirred.The case of an exactly equivalent amount of aluminium(III) chloride as the substrate resulted in good results.