75334-99-5

Upstream product

• 67-56-1 methanol 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 
• 149-73-5 trimethyl orthoformate 
• 19513-80-5 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-one 

Downstream Products

• 42718-22-9 N-[(methoxycarbonyl)(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 
• 151259-49-3 methyl N-p-tolylsulfonyl-2-imino-2-(p-methoxyphenyl)acetate 

Relevant academic research and scientific papers

Selective electrochemical C[sbnd]O bond cleavage of β-O-4 lignin model compounds mediated by iodide ion

The electrochemically oxidative cleavage of lignin β-O-4 model compounds mediated by iodide ion has been studied. The results indicate that electrolytic conditions play a predominant role in determining the distribution of cleavage products. The preparative-scale electrolysis proceeds in a simple undivided cell, employing a catalytic amount of NaI as the redox mediator and supporting electrolyte in methanol. Under these conditions, the Cβ[sbnd]O bond is selectively cleaved with 2,2-dimethoxy-2-arylacetaldehyde being the main product. In some cases, the reaction gives a good yield of cleavaged products. The results further demonstrate that the indirect electrolysis mediated by halide is a versatile approach for chemical transformation.

Diphenylsilane Reduction of C=O and C=N Bearing Electron-Withdrawing Group in the Presence of Aluminium(III) Chloride

Several α-keto esters and methyl N-p-tolylsulfonyl-2-aryl-2-iminoacetates were reduced to the corresponding α-hydroxy esters and methyl N-p-tolylsulfonyl-2-arylglycinates in high yields by a combination of aluminium(III) chloride and diphenylsilane under operating conditions in which diphenylsilane was added to the pre-formed substrate-aluminium(III) chloride complex in dichloromethane and the mixture stirred.The case of an exactly equivalent amount of aluminium(III) chloride as the substrate resulted in good results.

Oxidation of 1,3-Diphenyl-1,3-propanediones with Thallium(III) Nitrate in Methanol

On oxidation with thallium(III) nitrate in methanol, 1,3-diphenyl-1,3-propanediones 1 rearrange to give 3-oxo-2,3-diphenylpropanoic esters 2 and products derived therefrom.However, 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanediones 1h-k undergo oxidative cyclization to 2-aroyl-3(2H)-benzofuranones 5.The alkali and acid catalysed cleavage of 5 is discussed.