151287-95-5

Upstream product

• 13398-94-2 2-(3-hydroxyphenyl)ethanol 
• 141-78-6 ethyl acetate 
• 108-05-4 vinyl acetate 

Downstream Products

• 372522-90-2 2-allyloxy-4-(2-hydroxyethyl)benzaldehyde 
• 372522-92-4 2-allyloxy-4-(2-hydroxyethyl)benzonitrile 
• 372523-05-2 2-methoxy-5-methylbenzenesulfonic acid 3-[2-(3-allyloxy-4-cyanophenyl)ethoxy]phenyl ester 
• 372523-29-0 2,3-dichlorobenzenesulfonic acid 3-[2-(4-cyano-3-hydroxyphenyl)ethoxy]-5-ethylphenyl ester 
• 372523-10-9 2,5-dichlorobenzenesulfonic acid 3-[2-(3-allyloxy-4-cyanophenyl)ethoxy]-5-methylphenyl ester 
• 372523-16-5 2,3-dichlorobenzenesulfonic acid 3-[2-(3-allyloxy-4-cyanophenyl)ethoxy]-5-ethylphenyl ester 
• 372523-30-3 3,5-dichloro-2-methoxybenzenesulfonic acid 3-[2-(4-cyano-3-hydroxyphenyl)ethoxy]-5-ethylphenyl ester 
• 372523-17-6 3,5-dichloro-2-methoxybenzenesulfonic acid 3-[2-(3-allyloxy-4-cyanophenyl)ethoxy]-5-ethylphenyl ester 
• 372522-89-9 acetic acid 2-(4-formyl-3-hydroxyphenyl)ethyl ester 

Relevant academic research and scientific papers

SUBSTITUTED CYCLOPENTANES OR CYCLOPENTANONES AS THERAPEUTIC AGENTS

Therapeutic compounds, methods, and compositions are disclosed herein.

Alkylchlorotins grafted to cross-linked polystyrene beads by a -(CH 2)n spacer (n-4, 6, 11): Selective, clean and recyclable catalysts for transesterification reactions

Insoluble polystyrene grafted compounds of the type (P-H) (1-t)(P-(CH2)nSnBupCl 3-p,}t, (P-H)(1-t){P-(CH2) nSnBuO)t and (P-H)(1-t)[(P-(CH 2)nSnBuCl}2O]t/2, in which (P-H) is a cross-linked polystyrene; n=4, 6, and 11; p=0 and 1; and t the degree of functionalisation, were synthesised from Amberlite XE-305, a polystyrene cross-linked with divinylbenzene. The compounds were characterised by using elemental analysis, and IR, Raman, solid-state 117Sn NMR, and 1H and 119Sn high-resolution MAS NMR spectroscopy. The influence of the spacer length and the tin functionality on the catalytic activity of these compounds, as well as their recycling ability, was assessed in the transesterifica tion reaction of ethyl acetate with various alcohols. These studies showed significant differences in the activity of the catalysts interpreted in terms of changes in the mobility of the catalytic centres. Some of the supported catalysts could be recycled at least seven times without noticeable loss of activity. The residual tin content in the reaction products was found to be as low as 3 ppm.

Statistical molecular design, parallel synthesis, and biological evaluation of a library of thrombin inhibitors

A library of thrombin inhibitors has been designed using statistical molecular design. An aromatic scaffold was used, with three varied positions corresponding to three pockets at the active site of thrombin (the S-, P-, and D-pockets). The selection was

Lipase-catalysed chemoselective monoacetylation of hydroxyalkylphenols and chemoselective removal of a single acetyl group from their diacetates

It was demonstrated that Pseudomonas cepacia PS lipase adsorbed on Celite, has the ability to catalyse the chemoselective monoacetylation of various hydroxyalkylphenols or the chemoselective removal of a single acetyl group from the corresponding acetate.