151323-87-4Relevant articles and documents
HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE
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Page/Page column 39-40, (2010/11/17)
The present invention relates to a compound represented by a formula (I): wherein X is a group represented by or the like; Y is a group represented by or the like; and Ar1 is a group represented by or a pharmaceutically acceptable salt thereof.
ALKYLAMINOPYRIDINE DERIVATIVE
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Page/Page column 51; 52, (2011/01/11)
The present invention relates to a compound that is useful for treatment of, for example, hypertension, arteriosclerosis, bulimia and obesity because of having an antagonistic action to a neuropeptide Y receptor and is represented by formula (I) [wherein R1 represents hydrogen, cyano, or the like; R represents a group represented by formula (II); X1 represents C1-4 lower alkylene or the like; X2 represents lower alkylene or the like; and Het represents a 5-membered heteroaromatic ring that has at least one nitrogen atom and, in addition, one or two hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen atoms] or to a pharmaceutically acceptable salt thereof.
A New Synthesis of 3H-1,2-Dithiole-3-thiones
Curphey, Thomas J.,Joyner, H. Howard
, p. 3703 - 3706 (2007/10/02)
Exposure of 3-oxo dithioic acids to a solution of polysulfanes in liquid hydrogen sulfide gives 3H-1,2-dithiole-3-thiones in yields varying from poor to excellent.The method tolerates the presence of functional groups which are problematical for other met
Synthesis of 3H-1,2-dithiole-3-thiones by a novel oxidative cyclization
Curphey, Thomas J.,Joyner, H. Howard
, p. 7231 - 7234 (2007/10/02)
Reaction of 3-oxo dithioic acids with a combination of hexamethyldisilathiane and N-chlorosuccinimide in the presence of a catalytic amount of imidazole brings about oxidative ring closure to 3H-1,2-dithiole-3-thiones. Yields vary from poor to good.
