151476-40-3

Basic information

• Product Name: N-t-Boc-1-adamantylamine
• Synonyms: N-t-Boc-1-adamantylamine;N-t-Boc-1-aminoadamantane;N-t-Butoxycarbonyl-1-adamantylamine;Tricyclo[3.3.1.13,7]dec-1-ylcarbamic Acid 1,1-Dimethylethyl Ester;1-(Boc-amino)adamantane;N-Boc-1-adamantylamine;tert-Butyl N-tricyclo[3.3.1.13,7]dec-1-ylcarbamate;tert-butyl N-(1-adamantyl)carbamate
• CAS NO: 151476-40-3
• Molecular Formula: C₁₅H₂₅NO₂
• Molecular Weight: 251.36
• Product Categories: Aliphatics;Intermediates;Aliphatics, Intermediates
• Mol File: 151476-40-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 110-115°C
• Boiling Point: 351.3°C at 760 mmHg
• Flash Point: 166.2°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 4.16E-05mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: ?20°C
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: N-t-Boc-1-adamantylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-t-Boc-1-adamantylamine(151476-40-3)
• EPA Substance Registry System: N-t-Boc-1-adamantylamine(151476-40-3)

Safety Data

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 151476-40-3(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Intermediate for the preparation of Amantadine.

InChI:InChI=1/C15H25NO2/c1-14(2,3)18-13(17)16-15-7-10-4-11(8-15)6-12(5-10)9-15/h10-12H,4-9H2,1-3H3,(H,16,17)

Upstream product

• 5511-18-2 adamantane-1-carboxamide 
• 768-95-6 1-adamanthanol 
• 24886-73-5 1-Azidoadamantane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1660-04-4 1-acetyladamantane 
• 768-94-5 1-Adamantanamine 
• 828-51-3 1-Adamantanecarboxylic acid 

Downstream Products

• 19026-84-7 N-(adamantan-1-yl)benzamide 
• 1332305-36-8 N-(2,3,6-tri-O-benzoyl-4-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-β-D-glucopyranosyloxycarbonyl)-1-adamantylamine 
• 1332305-32-4 N-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyloxycarbonyl)-1-adamantylamine 
• 1332305-34-6 N-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyloxycarbonyl)-1-adamantylamine 
• 1332305-26-6 N-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyloxycarbonyl)-1-adamantylamine 

Relevant articles and documents

Transformation of Primary Carboxamides to N-(t-Butoxycarbonyl)amines Using CuBr2-LiOBut

The reaction of primary carboxamides with the copper(II) reagent prepared from copper(II) bromide and lithium t-butoxide gave the corresponding N-(t-butoxycarbonyl)amines in good to high yields.

Deacetylative Amination of Acetyl Arenes and Alkanes with C-C Bond Cleavage

The Br?nsted acid-catalyzed synthesis of primary amines from acetyl arenes and alkanes with C-C bond cleavage is described. Although the conversion from an acetyl group to amine has traditionally required multiple steps, the method described herein, which uses an oxime reagent as an amino group source, achieves the transformation directly via domino transoximation/Beckmann rearrangement/Pinner reaction. The method was also applied to the synthesis of γ-aminobutyric acids, such as baclophen and rolipram.

RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING A RESIST PATTERN, COMPOUND, AND POLYMER

A radiation-sensitive resin composition includes a first polymer that includes a repeating unit having an acid-labile group and becomes alkali-soluble upon dissociation of the acid-labile group, and a radiation-sensitive acid-generating agent. The acid-labile group has a structure shown by a general formula (1). R1 represents a methyl group or the like, R2 represents a hydrocarbon group that forms a cyclic structure, R3 represents a fluorine atom or the like, R4 represents a carbon atom, and n1 is an integer from 1 to 7.