151489-85-9

Basic information

• Product Name: (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine
• Synonyms: (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine;S-6,6'-dimethoxy-[1,1'-Biphenyl]-2,2'-diamine
• CAS NO: 151489-85-9
• Molecular Formula: C14H16N2O2
• Molecular Weight: 244.29
• Mol File: 151489-85-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine(151489-85-9)
• EPA Substance Registry System: (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine(151489-85-9)

Safety Data

• Hazardous Substances Data: 151489-85-9(Hazardous Substances Data)

Usage

General Description

(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine, also known as (S)-(+)-1,1'-Bi(2-naphthol), is a chiral diamine compound used in the synthesis of chiral ligands and catalysts. It is commonly employed in asymmetric catalysis for the enantioselective synthesis of various organic compounds. (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is a key building block in the production of pharmaceuticals, agrochemicals, and materials. It has two methoxy groups attached to the biphenyl core, and its chiral nature makes it a valuable chemical for controlling the stereochemistry of reactions in organic synthesis. Overall, (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is a versatile and important compound in the field of asymmetric synthesis and catalysis.

Upstream product

• 137465-71-5 2,2'-dimethoxy-6,6'-dinitrobiphenyl 
• 98991-08-3 2-iodo-1-methoxy-3-nitrobenzene 
• 197243-48-4 2-iodo-3-nitrophenol 
• 554-84-7 meta-nitrophenol 
• 101938-44-7 rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine 
• 603-85-0 2-Amino-3-nitrophenol 
• 102-56-7 2,5-dimethoxyaniline 
• 170959-02-1 2,5-dimethoxypivaloylaminobenzene 
• 536-90-3 m-Anisidine 
• 56619-93-3 N-(3-methoxyphenyl)pivalamide 
• 1313369-32-2 N,N'-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(2,2-dimethylpropanamide) 

Relevant articles and documents

Synthetic method for optically pure double-helix oligomeric tetra-benzocyclooctene substances

The invention discloses a synthetic method for optically pure double-helix oligomeric tetra-benzocyclooctene substances. The synthetic method comprises the following steps: (1) carrying out oxidative cross-coupling on diiodo dimethoxy biphenyl (51) and 2,2',6,6'-biphenyl tetrabromide (97) to obtain 1,16-dibromo-8,9-dimethoxy tetra-benzocyclooctene (96); (2) splitting the compound (96), thus obtaining optically pure (S, S)-96 and (R, R)-96; (3) taking the compound (96) as a raw material, synthesizing an intermediate (116) containing 6 benzene rings; (4) splitting the intermediate (116) to obtain (M)-116 and (P)-116; (5) making the optically pure (S, S)-96 and (M)-116 reacted to obtain target products, namely (M) -117, (M)-149 and (M)-150; and/or: making the (R, R)-96 and (P)-116 reacted to obtain target products, namely (P)-117, (P)-149 and (P)-150.

Chiral biphenylamide derivative: An efficient organocatalyst for the enantioselective synthesis of α-hydroxy phosphonates

The aldol reactions of α-keto phosphonates and aldehydes were facilitated by an axially chiral biphenylprolinamide under mild conditions, affording the synthetically and pharmaceutically useful products in high yields and excellent enantioselectivities.