10512-93-3

Basic information

• Product Name: Z-VAL-ONP
• Synonyms: BENZYLOXYCARBONYL-L-VALINE 4-NITROPHENYL ESTER;BENZYLOXYCARBONYL-L-VALINE P-NITROPHENYL ESTER;N-CBZ-L-Valine p-nitrophenyl ester N-Carbobenzyloxy-L-valine p-nitrophenyl ester;4-nitrophenyl N-[(benzyloxy)carbonyl]-L-valinate;Z-L-VALINE 4-NITROPHENYL ESTER 98+%;N-Benzyloxycarbonyl-L-valine-4-nitrophenyl ester;N-alpha-Benzyloxycarbonyl-L-valine p-nitrophenyl ester;Z-L-Val-ONp
• CAS NO: 10512-93-3
• Molecular Formula: C₁₉H₂₀N₂O₆
• Molecular Weight: 372.37
• EINECS: 234-047-5
• Product Categories: Amino Acid Derivatives
• Mol File: 10512-93-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 61 °C
• Boiling Point: 552.6°Cat760mmHg
• Flash Point: 288°C
• Appearance: /
• Density: 1.261g/cm³
• Vapor Pressure: 2.95E-12mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• PKA: 10.57±0.46(Predicted)
• BRN: 1895803
• CAS DataBase Reference: Z-VAL-ONP(CAS DataBase Reference)
• NIST Chemistry Reference: Z-VAL-ONP(10512-93-3)
• EPA Substance Registry System: Z-VAL-ONP(10512-93-3)

Safety Data

• WGK Germany: 3
• F: 8
• Hazardous Substances Data: 10512-93-3(Hazardous Substances Data)

Usage

General Description

Z-Val-ONP, also known numerically as 1680-31-1, is a chemical that falls into the category of biochemical and biologically active compounds. It includes peptide functionalities that commonly act as enzyme inhibitors or substrates. Its primary application is typically in biological systems, for research or pharmaceutical purposes. Its chemical formula is C29H34N4O9 and has a molecular weight of 590.6 g/mol. Data related to its toxicity or potential hazards is currently not available.

InChI:InChI=1/C19H20N2O6/c1-13(2)17(20-19(23)26-12-14-6-4-3-5-7-14)18(22)27-16-10-8-15(9-11-16)21(24)25/h3-11,13,17H,12H2,1-2H3,(H,20,23)/t17-/m0/s1

Upstream product

• 100-02-7 4-nitro-phenol 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 7693-46-1 4-Nitrophenyl chloroformate 
• 25887-81-4 bis(p-nitrophenyl)sulfite 

Downstream Products

• 79598-35-9 benzyloxycarbonylvalyltyrosine ethyl ester 
• 6461-15-0 N²-(N-benzyloxycarbonyl-L-valyl)-N⁵-(toluene-4-sulfonyl)-L-ornithine methyl ester 
• 52616-98-5 Cbz-Val-Leu-OtBu 
• 1999-88-8 methyl (S)-2-((S)-2-benzyloxycarbonyl-amino-3-methylbutyrylamino)-3-methylbutyrate 
• 51827-14-6 N-[(Phenylmethoxy)carbonyl]-L-valyl-L-proline methyl ester 
• 22221-75-6 N-(N-benzyloxycarbonyl-L-valyl)-glycine 
• 148743-43-5 N-benzyloxycarbonyl-L-valyl-L-phenylalaninol 
• 19542-54-2 N-benzyloxycarbonyl-L-valyl-L-valine 
• 91650-00-9 Cbz-L-Val-L-propinal 
• 1454891-33-8 N-(2-(4-(6-amino-9-ethyl-9H-purine-8-yl)-1H-1,2,3-triazol-1-yl)acetyl)-2-benzyloxycarbonylamino-3-methylbutanamide 
• 46339-96-2 L-N-cyclohexylvalinamide 
• 874190-42-8 Z-Leu-Val-Val-Tyr-Pro 

Relevant articles and documents

Thermodynamic and (1)H NMR Study of Proton Complex Formation of Histidine-containing Cyclodipeptides in Aqueous Solution

A thermodynamic and (1)H NMR study of proton complex formation in aqueous solution of some L-histidine-containing cyclic L-dipeptides has been carried out.The enthalpic and entropic changes associated with protonation of the cyclodipeptides, obtained by potentiometric and calorimetric measurements, together with the (1)H NMR data and NOESY experiments, enable the role played by non-covalent interactions in proton complex formation to be assessed.In addition, a comparison with c(Gly-His) permits the influence of side-chain residues on the conformation of protonated species to be observed.

Specificity of -chymotrypsin. The -chymotrypsin-catalyzed hydrolysis of N-acylamino acid p-nitrophenyl esters.

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