15150-39-7

Usage

Uses

Used in Pharmaceutical Industry:
4-methylphenyl chloroacetate is used as a synthetic intermediate for the production of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 4-methylphenyl chloroacetate serves as an essential intermediate in the synthesis of pesticides and other agrochemical products. Its role in creating effective and targeted solutions helps to improve crop protection and contribute to sustainable agriculture practices.
Used as a Hazardous Material in Safety Protocols:
Due to its potential to cause irritation and require specific handling procedures, 4-methylphenyl chloroacetate is used as a reference material in safety protocols and training programs within laboratories and industries. This ensures that personnel are well-equipped to handle and dispose of the chemical safely, minimizing risks to health and the environment.

Upstream product

• 106-44-5 p-cresol 
• 42345-82-4 (E)-1,2-dichloro-1-ethoxy-ethene 
• 79-11-8 chloroacetic acid 
• 79-04-9 chloroacetyl chloride 
• 937-62-2 p-tolyl chloroformate 
• 274679-39-9 p-tolyl 2-diazoacetate 

Downstream Products

• 73260-80-7 (Bis-p-tolyloxycarbonylmethyl-phosphanyl)-acetic acid p-tolyl ester 
• 119929-71-4 [4-(2,3,4-Trimethoxy-benzyl)-piperazin-1-yl]-acetic acid p-tolyl ester 
• 22307-94-4 2-chloroacetyl-4-methylphenol 
• 99984-12-0 2,6-bis-chloroacetyl-4-methyl-phenol 
• 54120-66-0 5-methyl-benzofuran-3-one 
• 305834-64-4 1-(2-acetoxy-5-methyl-phenyl)-2-chloro-ethanone 

Relevant academic research and scientific papers

MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF

The disclosure relates to compounds and pharmaceutical compositions capable of modulating the hydroxysteroid 17-beta dehydrogenase (HSD17B) family member proteins including inhibiting the HSD17B member proteins, e.g. HSD17B13. The disclosure further relates to methods of treating liver diseases, disorders, or conditions with the compounds and pharmaceutical compositions disclosed herein, in which the HSD17B family member protein plays a role.

Synthesis and antibacterial activity of 3-benzylamide derivatives as FtsZ inhibitors

The emergence and spread of multidrug-resistant strains of the human pathological bacteria are generating a threat to public health worldwide. In the current study, a series of PC190723 derivatives was synthesized and investigated for their antimicrobial activity. The compounds exhibited good activity against several Gram-positive bacteria as determined by comparison of diameters of the zone of inhibition of test compounds and standard antibiotics. Compound 9 with a fluorine substitution on the phenyl ring showed the best antibacterial activity in the series against M. smegmatis with the zone ratio of 0.62, and against S. aureus with the zone ratio of 0.44. The results from this study indicate that based on the unique 3-methoxybenzamide pharmacophore, compound 9 may represent a promising lead candidate against Gram-positive bacteria that are worthy of further investigation

Chemistry of diazopolycarbonyl compounds: V. Synthesis, structure, and chemical characteristics of aryl diazoacetates

Aryl diazoacetates were prepared, and basing on spectral data and quantum-chemical calculations cis-trans isomerism thereof was proved. The reactions of diazoesters with hydrochloric and sulfuric acids, triphenylphosphine, and dinitrogen tetroxide resulted respectively in aryl chloroacetates, bis(aryloxy-carbonylmethyl) sulfates, triphenylphosphoranylidenehydrazones of aryl 2-oxoethanoates, and N-oxides of diaryl 1,2,5-oxadiazole-3,4-dicarboxylates.