1515895-92-7Relevant academic research and scientific papers
Synthesis and application of chalcones to the preparation of heterocyclic structures
Velikorodov,Ionova,Temirbulatova,Titova,Stepkina
, p. 1610 - 1616 (2014/02/14)
Condensation of methyl N-(4-acetylphenyl)carbamate with aromatic aldehydes in basic and acid environment, and also with hetarylaldehydes in the presence of bases afforded chalcones with the carbamate function. Under the conditions of basic catalysis a nucleophilic substitution was observed of a methoxy group in the carbamate moiety of the chalcone for an ethoxy group. The reactions of the obtained chalcones with hydrazine hydrate, isonicotinic acid hydrazide, guanidine and hydroxylamine hydrochlorides, thiourea, and selenium dioxide furnished the corresponding derivatives of pyrazole, oxazole, pyrimidine, and selenadiazole. Pleiades Publishing, Ltd., 2013.
