50890-51-2

Basic information

• Product Name: 1-chloro-2-(methylsulfonyl)ethane(SALTDATA: FREE)
• Synonyms: 1-chloro-2-(methylsulfonyl)ethane(SALTDATA: FREE);2-chloroethylsulfonylmethane;Acetyldimethylcyclopentenyl retinoic acid;NSC 191945;1-Chloro-2-(methylsulfonyl);1-chloro-2-(methylsulfonyl)ethane(SALTDATA
• CAS NO: 50890-51-2
• Molecular Formula: C₃H₇ClO₂S
• Molecular Weight: 142.60448
• Mol File: 50890-51-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 292.8 °C at 760 mmHg
• Flash Point: 130.9 °C
• Appearance: /
• Density: 1.29 g/cm³
• Vapor Pressure: 0.00315mmHg at 25°C
• Refractive Index: 1.448
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-chloro-2-(methylsulfonyl)ethane(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-(methylsulfonyl)ethane(SALTDATA: FREE)(50890-51-2)
• EPA Substance Registry System: 1-chloro-2-(methylsulfonyl)ethane(SALTDATA: FREE)(50890-51-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 50890-51-2(Hazardous Substances Data)

Usage

General Description

1-Chloro-2-(methylsulfonyl)ethane is a chemical compound with the molecular formula C3H7ClO2S. It is commonly referred to as MES and is used as a sulfonating agent in organic synthesis. MES is a colorless liquid with a slightly sweet odor and is soluble in water, ethanol, and ether. It is considered to be a mild irritant to the skin, eyes, and respiratory system and should be handled with caution. MES is commonly used in the pharmaceutical industry as a buffer and in the production of dyes and pigments. It is important to follow proper safety protocols when working with this chemical, including wearing protective equipment and handling it in a well-ventilated area.

InChI:InChI=1/C3H7ClO2S/c1-7(5,6)3-2-4/h2-3H2,1H3

Upstream product

• 542-81-4 sulfure de methyle et de 2-chloroethyle 
• 15205-66-0 2-(methylsulfonyl)ethyl alcohol 

Downstream Products

• 71350-93-1 (2-Methanesulfonyl-ethylsulfanylmethyl)-benzene 
• 7647-01-0 hydrogenchloride 
• 15205-66-0 2-(methylsulfonyl)ethyl alcohol 
• 49773-20-8 2-Methanesulfonyl-ethylamine 
• 3383-79-7 2-(2-naphthyloxy)-1-chloroethane 
• 1257707-09-7 1-(2-methanesulfonyl-ethyl)-4-(3-nitro-phenyl)-1,2,3,6-tetrahydro-pyridine 
• 209966-88-1 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[2-(methylthio)ethylamino]-4-ethylsulfinyl-1H-pyrazole-3-carbonitrile 
• 209966-89-2 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[2-(methylthio)ethylamino]-4-methylsulfinyl-1H-pyrazole-3-carbonitrile 
• 3680-02-2 methyl ethenyl sulphone 
• 1093967-37-3 1-(2-(methylsulfonyl)ethyl)-3-nitro-1H-pyrazole 

Relevant articles and documents

JNK inhibitor as well as pharmaceutical composition and application thereof

The invention provides a compound represented by a formula (I), racemates, stereoisomers, tautomers, isotope markers, solvates, polymorphic substances, nitrogen oxides, or pharmaceutically acceptablesalts thereof, and application as a JNK inhibitor. The invention also provides a preparation method of the compound shown in the formula (I), a pharmaceutical composition containing the compound shownin the formula (I), and application of the compound shown in the formula (I) to preparation of a medicine, and the medicine is used for treating diseases which can be treated by inhibiting the activity of JNK.

HETEROCYCLIC COMPOUND

The present invention provides an agent for the prophylaxis or treatment of autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, multiple sclerosis, systemic lupus erythematosus etc.) and the like, which has a superior Tyk2 inhibitory action. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.

KINASE INHIBITOR COMPOUNDS

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.