Synthetic studies on bryostatins, antineoplastic metabolites: Convergent synthesis of the C1-C16 fragment shared by all of the bryostatin family

Article abstract of DOI:10.1016/S0040-4039(00)74063-9

The C₁-C₁₆ fragment of bryostatins could successfully be synthesized by tandem connection of the appropriate three fragments and effective introduction of the α,β-unsaturated esters at the C₁₃ position.