1530-73-0

Basic information

• Product Name: N,N'-BIS(P-TOLUOYL)HYDRAZINE
• Synonyms: N,N'-BIS(P-TOLUOYL)HYDRAZINE;di-p-toluohydrazide;1,2-Bis(p-methylbenzoyl)hydrazine;1,2-Di(4-methylbenzoyl)hydrazine;4-Methylbenzoic acid 2-(4-methylbenzoyl) hydrazide;4-methyl-N'-(4-methylphenyl)carbonyl-benzohydrazide;N,Nzzhlxy-Bis(p-toluoyl)hydrazine;4-methyl-N'-(4-methylbenzoyl)benzohydrazide (non-preferred name)
• CAS NO: 1530-73-0
• Molecular Formula: C16H16N2O2
• Molecular Weight: 268.31
• EINECS: 216-232-2
• Mol File: 1530-73-0.mol
• Article Data: 24

Chemical Properties

• Melting Point: 253-254 °C
• Boiling Point: 527.5°Cat760mmHg
• Flash Point: 207.8°C
• Appearance: /
• Density: 1.163g/cm³
• PKA: 10.67±0.23(Predicted)
• CAS DataBase Reference: N,N'-BIS(P-TOLUOYL)HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-BIS(P-TOLUOYL)HYDRAZINE(1530-73-0)
• EPA Substance Registry System: N,N'-BIS(P-TOLUOYL)HYDRAZINE(1530-73-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 1530-73-0(Hazardous Substances Data)

Usage

General Description

N,N'-BIS(P-TOLUOYL)HYDRAZINE is a chemical compound with the molecular formula C22H26N4O2. It is a hydrazone derivative and a substituted hydrazine compound. This chemical is commonly used as a starting material in the synthesis of other organic compounds, and it has been studied for its potential use in pharmaceuticals and as a reagent in chemical reactions. N,N'-BIS(P-TOLUOYL)HYDRAZINE is known for its high reactivity and ability to form stable complexes with various metals, making it useful in coordination chemistry and chelation processes in chemical and biological systems. However, it is important to handle this compound with care due to its potential hazards and toxicity.

Upstream product

• 3619-22-5 p-toluic hydrazide 
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• 18038-65-8 trichloro-(1,1,2-tribromo-ethyl)-silane 
• 13222-85-0 p-methylbenzoic anhydride 
• 50-00-0 formaldehyd 
• 558-13-4 carbon tetrabromide 
• 75-02-5 1-fluoroethylene 
• 194033-79-9 2,2,3-tribromopropanoic acid 
• 27949-36-6 1-dibromo-2-chloroethane 

Downstream Products

• 10465-75-5 1,2-Bis(4-methylbenzoyl)diazene 
• 2491-91-0 2,5-di-p-tolyl-1,3,4-oxadiazole 
• 16112-33-7 2,5-bis(4-methylphenyl)-1,3,4-thiadiazole 
• 3005-30-9 3,5-di-p-tolyl-4H-{1,2,4}triazole 
• 1312991-48-2 6-methyl-3,4-diphenylisoquinolin-1(2H)-one 
• 1874-47-1 2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole 
• 58370-38-0 diethyl 4-(5-(4-(diethoxyphosphino)methylphenyl)-1,3,4-oxadiazol-2-yl)-benzyl-phosphonate 

Relevant articles and documents

Oxidation of Hydrazides Using Sodium Perborate: Formation of N,N′-Diacylhydrazines

Substituted aromatic hydrazides react very smoothly with sodium perborate in glacial acetic acid at room temperature to give N,N′-diacylhydrazines in excellent yields and purity.

Polymer light-emitting diodes based on a bipolar transporting luminescent polymer

A soluble electroluminescent polymer containing hole-deficient triphenylamine and electron-deficient oxadiazole units in the main chains has been designed and studied. The design is based on the consideration that the triphenylamine group possesses good hole-transporting property and the oxadiazole unit is known to be of electron-transporting character. Because of the good bipolar transporting performance, the brightness and electroluminescent efficiency are significantly improved and the turn-on voltage is reduced compared with a similar polymer without the electron-deficient oxadiazole units in the main chains. For a device with configuration ITO/PEDOT/polymer/CsF/Al, a maximum brightness of 3600 cd m-2 and a maximum luminescent efficiency of 0.65 cd A-1 (quantum efficiency of 0.3%) were obtained in the polymer with oxadiazole units, about 15 times brighter and 15 times more efficient than the corresponding polymer without oxadiazole units.

Synthesis and characterization of a novel charge transfer compound with large three-photon absorption cross section

A new intramolecular charge transfer compound containing diethylamino group as electronic donor and oxadiazole group as electronic acceptor has been synthesized using Wittig-Horner reaction. This long conjugated molecule has large three-photon absorption cross section excited at 1.06 μm lasing.

Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies

Benzohydrazide derivatives 1–43 were synthesized via “one-pot” reaction and structural characterization of these synthetic derivatives was carried out by different spectroscopic techniques such as 1H NMR and EI-MS. The synthetic molecules were evaluated for their in vitro urease inhibitory activity. All synthetic derivatives showed good inhibitory activities in the range of (IC50 = 0.87 ± 0.31–19.0 ± 0.25 μM) as compared to the standard thiourea (IC50 = 21.25 ± 0.15 μM), except seven compounds 17, 18, 23, 24, 29, 30, and 41 which were found to be inactive. The most active compound of the series was compound 36 (IC50 = 0.87 ± 0.31 μM) having two chloro groups at meta positions of ring A and methoxy group at para position of ring B. The structure–activity relationship (SAR) of the active compounds was established on the basis of different substituents and their positions in the molecules. Kinetic studies of the active compounds revealed that compounds can inhibit enzyme via competitive and noncompetitive modes. In silico study was also performed to understand the binding interactions of the molecules (ligand) with the active site of enzyme.

Method for producing 1,1-dibromo-1-fluoroethane

The present invention addresses the problem of providing a production method which enables 1,1-dibromo-1-fluoroethane to be produced in a simple and sustained manner. The present invention provides a method for producing 1,1-dibromo-1-fluoroethane, said method comprising step A of reacting 1,1-dibromoethylene with hydrogen fluoride to produce 1,1-dibromo-1-fluoroethane.