13222-85-0Relevant academic research and scientific papers
Synthesis of symmetric anhydrides using visible light-mediated photoredox catalysis
Konieczynska, Marlena D.,Dai, Chunhui,Stephenson, Corey R. J.
, p. 4509 - 4511 (2012)
A new approach to anhydride formation is reported via activation of C-O bonds by the Vilsmeier-Haack reagent formed by Ru(bpy)3Cl2 and CBr4 in DMF. Various aryl and alkyl carboxylic acids are converted to the corresponding anhydrides in excellent yields.
Cu-MOF: An efficient heterogeneous catalyst for the synthesis of symmetric anhydrides: Via the C-H bond activation of aldehydes
Ahmadzadeh, Zahra,Mokhtari, Javad,Rouhani, Morteza
, p. 24203 - 24208 (2018)
In this paper, an efficient and straightforward synthetic approach for the preparation of a number of symmetric carboxylic anhydrides was reported using Cu2(BDC)2(DABCO) as an efficient heterogeneous catalyst via the C-H bond activation of aldehydes with excellent yields and simple work up. This C-H bond activation reaction appears simple and convenient, has a wide substrate scope and makes use of cheap, abundant, and easily available reagents. The Cu-MOF catalyst was recycled and reused four times without any loss of catalytic activity.
Synthesis of anhydrides from acyl chlorides under ultrasound condition
Hu, Yulai,Wang, Jin-Xian,Li, Shihua
, p. 243 - 248 (1997)
A convenient and general method for the synthesis of symmetrical anhydrides under ultrasound conditions is described.
Synthesis, molecular docking, and pharmacological evaluation of N-(2-(3,5-dimethoxyphenyl)benzoxazole-5-yl)benzamide derivatives as selective COX-2 inhibitors and anti-inflammatory agents
Kaur, Avneet,Pathak, Dharam P.,Sharma, Vidushi,Wakode, Sharad
, (2018)
A series of N-(2-(3,5-dimethoxyphenyl)benzoxazole-5-yl)benzamide derivatives (3am) was synthesized and evaluated for their in vitro inhibitory activity against COX-1 and COX-2. The compounds with considerable in vitro activity (IC50 50 values in the range of 0.06–0.71 μM. The in vivo anti-inflammatory activity of these six compounds (3a, 3b, 3d, 3g, 3j, and 3k) was assessed by the carrageenan-induced rat paw edema method. Compounds 3d (84.09%), 3g (79.54%), and 3a (70.45%) demonstrated significant anti-inflammatory activity compared to the standard drug ibuprofen (65.90%) and were also found to be safer than ibuprofen, by ulcerogenic studies. A docking study was done using the crystal structure of human COX-2, to understand the binding mechanism of these inhibitors to the active site of COX-2.
FACILE CONVERSION OF AMIDES TO THE ACIDS AND/OR ANHYDRIDES USING DINITROGEN TETROXIDE
Kim, Yong Hae,Kim, Kweon,Park, Young Jun
, p. 3893 - 3894 (1990)
Carboxamides and sulfonamides were reacted with dinitrogen tetroxide to give the corresponding acids, while such as N-bromoamides and hydroxamic acids were also converted to the corresponding acids together with their anhydrides.
Efficient Preparation of 2-Deoxy-3,5-di-O-p-toluoyl-α-D- ribofuranosyl Chloride
Dhimitruka, Ilirian,SantaLucia Jr., John
, p. 335 - 337 (2004)
An efficient method for the synthesis of 1-O-methyl-3,5-di-O-p-toluoyl-2- deoxy-α/β-D-ribose is described. Upon treatment with HCl, 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribofuranosyl chloride, previously unstable, was produced as a white solid, stable in air indefinitely.
OXYGEN ATOM TRANSFER REACTION. THE REACTION OF CARBONYL COMPOUNDS WITH DIOXYGEN COMPLEXES
Aida, Shun'ichi,Ohta, Hiroyuki,Kamiya, Yoshio
, p. 1639 - 1642 (1981)
The reaction of peroxobis(triphenylphosphine)platinum with benzil or benzoic anhydride gave benzoic anhydride or benzoyl peroxide respectively.The scope of the above reactions is described.
Efficient synthesis of symmetrical anhydrides by cross dehydrogenative coupling of aryl aldehydes over CuFe2O4 nanoparticles
Eidi, Esmaiel,Kassaee, Mohamad Z.,Nasresfahani, Zahra
, p. 461 - 468 (2021)
Nano copper ferrite catalyst is prepared and characterized by scanning electron microscopy, energy dispersive X-ray, X-ray diffraction, vibrational sample magnetometry, and Fourier transform infrared. The catalytic activity is probed for cross-dehydrogenative coupling of aromatic aldehydes in the presence of tert-butyl hydroperoxide as the oxidant. This catalytic protocol appears as a simple, rather cheap, clean, and efficient practical strategy for the synthesis of symmetrical anhydrides, with proper efficiency (66%). The catalyst can be easily separated from the reaction mixture by an external magnet and reused several times in subsequent reactions, without any measurable loss of its efficiency. Graphic abstract: [Figure not available: see fulltext.]
Simple preparation of symmetrical carboxylic acid anhydrides by means of Na2CO3/SOCl2
Kazemi,Kiasat,Mombaini
, p. 3219 - 3223 (2007)
A convenient and general method for the synthesis of symmetrical carboxylic acid anhydrides using sodium carbonate/thionyl chloride is described. Copyright Taylor & Francis Group, LLC.
Oxidative self-coupling of aldehydes in the presence of CuCl2/TBHP system: Direct access to symmetrical anhydrides
Saberi, Dariush,Shojaeyan, Fatemeh,Niknam, Khodabakhsh
, p. 566 - 569 (2016)
A simple synthesis of symmetrical anhydrides has been developed. Using tert-butylhydroperoxide (TBHP) as the oxidant and copper(II) chloride as the catalyst in acetonitrile, various aromatic and heteroaromatic aldehydes were reacted to provide symmetrical anhydrides in modest to good yields.
