153063-58-2

Upstream product

• 67-56-1 methanol 
• 145041-33-4 S-tert-butyl (2R,3R)-2-benzyloxy-3-hydroxy-3-phenylpropanethioate 

Downstream Products

• 153000-30-7 methyl (2R,3R)-2-benzyloxy-3-tert-butyldimethylsilyloxy-3-phenylpropanoate 
• 154136-25-1 methyl (2R,3S)-2-benzyloxy-3-tert-butoxycarbonylamino-3-phenylpropanoate 
• 145041-37-8 methyl (2R,3S)-3-benzoylamino-2-benzyloxy-3-phenylpropanethioate 
• 124605-42-1 methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 153000-32-9 (R)-5-[(1R,2S,3R)-2-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-3-phenyl-propyl]-5H-furan-2-one 
• 153000-31-8 (2R,3R)-2-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-propionaldehyde 
• 153000-34-1 (+)-(1'S,2'R,3'R,4R)-4-(2'-benzyloxy-1',3'-dihydroxy-3'-phenylpropyl)-2-buten-4-olide 
• 153000-33-0 (+)-(1'S,2'R,3'R,4R)-4-(1',2',3'-trihydroxy-3'-phenylpropyl)-2-buten-4-olide 

Relevant academic research and scientific papers

Highly stereocontrolled asymmetric syntheses of taxol and taxotere C-13 side chain analogues

Asymmetric aldol reaction of (+)-tricarbonyl(η6-2-trimethylsilylbenzaldehyde)chromium(0) complex (4) with titanium enolate of S-tert-butyl benzyloxyethanethioate (10) provided, after consecutive desilylation and decomplexation, anti-aldol product 15 in a highly stereo selective manner. Anti-product 15 was subsequently converted to (2R,3S)-N-benzoyl- and N-tert-butoxycarbonyl-3-phenylisoserine methyl esters (23 and 24), C-13 side chain analogues of taxol (1) and taxotere (2).

An optically active chromium(0)-complexed benzaldehyde derivative in organic synthesis: A highly stereocontrolled total synthesis of (+)-goniofufurone

An antitumor styryl-lactone, (+)-goniofufurone was synthesized in a highly diastereoselecdve manner from (+)-tricarbonyl(η6-2-trimethylsilylbenzaldehyde)chromium(0) complex through stereoselective aldol reactions as crucial steps.