153186-14-2

Upstream product

• 63593-03-3 1,2-O-isopropylidene-3-O-benzyl-4-hydroxymethyl-α-D-ribofuranose 
• 153186-10-8 ((3aR,5R,6S,6aR)-6-(benzyloxy)-5-((benzyloxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 
• 100-44-7 benzyl chloride 

Downstream Products

• 153186-30-2 N⁶-benzoyl-2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyladenosine 
• 153186-25-5 2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyl-β-D-ribofuranosylthymine 
• 153186-24-4 2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyluridine 
• 160766-52-9 3',5'-di-O-benzyl-4'-C-methyladenosine 
• 153186-15-3 1,2-di-O-acetyl-3,5-di-O-benzyl-4-C-methyl-α-D-ribofuranose 
• 153186-16-4 1,2,5-di-O-acetyl-3-O-benzyl-4-C-methyl-α-D-ribofuranose 
• 153186-26-6 1-(4-C-methyl-β-D-ribofuranosyl)-uracil 
• 153186-29-9 4'-C-methylcytidine 
• 149017-69-6 (3aR,5R,6S,6aR)-6-(benzyloxy)-5-(benzyloxymethyl)-2,2,5-trimethyltetrahydrofuro[2,3-d][1,3]dioxole 

Relevant academic research and scientific papers

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-d

Synthesis of 4'-C-methylnucleosides.

Several 4'-C-methylnucleosides were prepared. 1H-NMR studies on these nucleotides showed that they have the 3'-exo furanose ring conformation different from the 3'-endo conformation of natural nucleosides.